Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: at a glance
MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …
placed a strong emphasis on cutting-edge nanostructured materials technologies to …
TME-targeted approaches of brain metastases and its clinical therapeutic evidence
The tumor microenvironment (TME), which includes both cellular and non-cellular elements,
is now recognized as one of the major regulators of the development of primary tumors, the …
is now recognized as one of the major regulators of the development of primary tumors, the …
Novel localization of folate transport systems in the murine central nervous system
Background Folates are a family of B9 vitamins that serve as one-carbon donors critical to
biosynthetic processes required for the development and function of the central nervous …
biosynthetic processes required for the development and function of the central nervous …
CNS drug delivery in stroke: improving therapeutic translation from the bench to the bedside
PT Ronaldson, EI Williams, RD Betterton, JA Stanton… - Stroke, 2024 - Am Heart Assoc
Drug development for ischemic stroke is challenging as evidenced by the paucity of
therapeutics that have advanced beyond a phase III trial. There are many reasons for this …
therapeutics that have advanced beyond a phase III trial. There are many reasons for this …
Dysfunction of ABC transporters at the surface of BBB: potential implications in intractable epilepsy and applications of nanotechnology enabled drug delivery
Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
Regulation of folate transport at the mouse arachnoid barrier
V Sangha, S Aboulhassane, R Bendayan - Fluids and Barriers of the CNS, 2024 - Springer
Background Folates are a family of B9 vitamins essential for normal growth and
development in the central nervous system (CNS). Transport of folates is mediated by three …
development in the central nervous system (CNS). Transport of folates is mediated by three …
CNS Drug Delivery in Stroke: Organic Anion Transporting Polypeptide (OATP)-Mediated Delivery of Atorvastatin Is a Requirement for Neuroprotection
EI Williams - 2024 - search.proquest.com
Stroke is the 5 th most common cause of death and the leading cause of long-term disability
in the United States. Drug development for ischemic stroke is challenging as evidenced by …
in the United States. Drug development for ischemic stroke is challenging as evidenced by …