[HTML][HTML] The continued threat of emerging flaviviruses

TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

[HTML][HTML] Zika virus infection—after the pandemic

D Musso, AI Ko, D Baud - New England Journal of Medicine, 2019 - Mass Medical Soc
Zika Virus and Its Associated Diseases Zika is a mosquito-borne flavivirus that can cause
congenital defects, including microcephaly. Although most Zika virus infections are …

Field-deployable viral diagnostics using CRISPR-Cas13

C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh… - Science, 2018 - science.org
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

[HTML][HTML] The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

[HTML][HTML] The Zika virus epidemic in Brazil: from discovery to future implications

R Lowe, C Barcellos, P Brasil, OG Cruz… - International journal of …, 2018 - mdpi.com
The first confirmed case of Zika virus infection in the Americas was reported in Northeast
Brazil in May 2015, although phylogenetic studies indicate virus introduction as early as …

Biochemistry and molecular biology of flaviviruses

NJ Barrows, RK Campos, KC Liao, KR Prasanth… - Chemical …, 2018 - ACS Publications
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

[HTML][HTML] We shouldn't worry when a virus mutates during disease outbreaks

ND Grubaugh, ME Petrone, EC Holmes - Nature microbiology, 2020 - nature.com
Mutation. The word naturally conjures fears of unexpected and freakish changes. Ill-
informed discussions of mutations thrive during virus outbreaks, including the ongoing …

[HTML][HTML] An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

H Xia, H Luo, C Shan, AE Muruato, BTD Nunes… - Nature …, 2018 - nature.com
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …

Arboviruses: A global public health threat

M Girard, CB Nelson, V Picot, DJ Gubler - Vaccine, 2020 - Elsevier
Abstract A conference on «ARBOVIRUSES, A GLOBAL PUBLIC HEALTH THREAT» was
organized on June 20–22, 2018 at the Merieux Foundation Conference Center in Veyrier du …

[HTML][HTML] Aedes Mosquitoes and Aedes-Borne Arboviruses in Africa: Current and Future Threats

D Weetman, B Kamgang, A Badolo, CL Moyes… - International journal of …, 2018 - mdpi.com
The Zika crisis drew attention to the long-overlooked problem of arboviruses transmitted by
Aedes mosquitoes in Africa. Yellow fever, dengue, chikungunya and Zika are poorly …