The concept of 'idiopathic'Parkinson's disease (PD) as a single entity has been challenged
with the identification of several clinical subtypes, pathogenic genes and putative causative …

Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …

Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia
nigra leading to disabling deficits. Dopamine neuron grafts may provide a significant …

Magnetic particle imaging (MPI) has recently emerged as a promising non-invasive imaging
technique because of its signal linearly propotional to the tracer mass, ability to generate …

Human pluripotent stem cells show considerable promise for applications in regenerative
medicine, including the development of cell replacement paradigms for the treatment of …

The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction
in Parkinson's disease, which makes cell replacement a promising therapeutic approach …

Following Alzheimer's, Parkinson's disease (PD) is the second-most common
neurodegenerative disorder, sharing an unclear pathophysiology, a multifactorial profile …

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder
characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy …

Brain tumors are one of the most mortal cancers, leading to many deaths among kids and
adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor …

Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are
involved in movement control and reward-related cognition. In Parkinson's disease …