Molecular dynamics (MD) simulation has been widely used in the field of biomedicine to
study the conformational transition of proteins caused by mutation or ligand …

Malignant melanoma is one of the most common tumours and has the highest mortality rate
of all types of skin cancers worldwide. Traditional and novel therapeutic approaches …

Abstract Ethnopharmacological relevance Dendrobium chrysotoxum Lindl, a well-known
traditional Chinese medicinal herb used in the treatment of gastric disease, is distinguished …

The progression of urothelial bladder cancer (UC) is a complicated multi-step process. We
perform a comprehensive multi-omics analysis of 448 samples from 190 UC patients …

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current
knowledge of cancer science and clinical oncology practice. This all-new edition is the …

Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is highly infectious and
pathogenic. Among patients with severe SARS‑CoV‑2‑caused by corona virus disease 2019 …

RAS oncogenes are among the most commonly mutated proteins in human cancers. They
regulate a wide range of effector pathways that control cell proliferation, survival …

Cisplatin is a common chemotherapeutic drug that has been used to treat of numerous
tumors, including testicular, lung, bladder, ovarian, liver and head and neck cancers …

Background Sotorasib is the first KRASG12C inhibitor approved by the US Food and Drug
Administration for treating KRASG12C-mutant non-small-cell lung cancer (NSCLC). Clinical …

Hepatoblastoma is the most common malignant liver cancer in childhood. The etiology of
hepatoblastoma remains obscure. Hepatoblastoma is closely related to genetic syndromes …