Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Clinically, antibiotics are widely used to treat infectious diseases; however, excessive drug
abuse and overuse exacerbate the prevalence of drug-resistant bacterial pathogens …

Thirteen fused pyridine derivatives have been designed, synthesized and characterized by 1
H NMR, 13 C NMR and IR spectral data and elemental analysis. Their in vitro antimicrobial …

Antimicrobial peptides (AMPs) in insects have the potential to be developed as
chemotherapy agents against numerous microbial species. This article reviewed the existing …

The emerging antibiotic resistance has been named by the World Health Organization
(WHO) as one of the top 10 threats to public health. Notably, methicillin‐resistant …

Peptidomimetics are a class of compounds with promising pharmacological properties.
Peptidomimetics reduce limitations of peptides including low bioavailability, poor stability …

Bacterial infections have been a serious threat to mankind throughout history. Natural
antimicrobial peptides (AMPs) and their membrane disruption mechanism have generated …

The enzymatic cascades for ubiquitin transfer regulate key cellular processes and are the
intense focus of drug development for treating cancer and neurodegenerative diseases. E1 …

There is an urgent need to develop novel antibiotic agents that can combat emerging drug
resistance. Herein, we report the design and investigation of a class of short dimeric …