[HTML][HTML] Optimal control theory for personalized therapeutic regimens in oncology: Background, history, challenges, and opportunities

AM Jarrett, D Faghihi, DA Hormuth, EABF Lima… - Journal of clinical …, 2020 - mdpi.com
Optimal control theory is branch of mathematics that aims to optimize a solution to a
dynamical system. While the concept of using optimal control theory to improve treatment …

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer (HYPO-RT-PC): patient-reported quality-of-life outcomes of a randomised …

P Fransson, P Nilsson, A Gunnlaugsson… - The Lancet …, 2021 - thelancet.com
Summary Background The HYPO-RT-PC trial compared conventionally fractionated
radiotherapy with ultra-hypofractionated radiotherapy in patients with localised prostate …

[HTML][HTML] Single-fraction stereotactic body radiation therapy: a paradigm during the coronavirus disease 2019 (COVID-19) pandemic and beyond?

SSW Ng, MS Ning, P Lee, RA McMahon, S Siva… - Advances in Radiation …, 2020 - Elsevier
Purpose Owing to the coronavirus disease 2019 (COVID-19) pandemic, radiation oncology
departments have adopted various strategies to deliver radiation therapy safely and …

ESTRO ACROP consensus guideline on the use of image guided radiation therapy for localized prostate cancer

P Ghadjar, C Fiorino, PM af Rosenschöld… - Radiotherapy and …, 2019 - Elsevier
Use of image-guided radiation therapy (IGRT) helps to account for daily prostate position
changes during radiation therapy for prostate cancer. However, guidelines for the use of …

Magnetic resonance-guided stereotactic radiotherapy for localized prostate cancer: final results on patient-reported outcomes of a prospective phase 2 study

SU Tetar, AME Bruynzeel, SS Oei, S Senan… - European Urology …, 2021 - Elsevier
Background The recent introduction of magnetic resonance-guided radiation therapy
(MRgRT) has allowed improved treatment planning and delivery of stereotactic body …

[HTML][HTML] Impact of hydrogel peri-rectal spacer insertion on prostate gland intra-fraction motion during 1.5 T MR-guided stereotactic body radiotherapy

F Cuccia, R Mazzola, L Nicosia, V Figlia… - Radiation …, 2020 - Springer
Background The assessment of organ motion is a crucial feature for prostate stereotactic
body radiotherapy (SBRT). Rectal spacer may represent a helpful device in order to …

ESTRO-ACROP recommendations for evidence-based use of androgen deprivation therapy in combination with external-beam radiotherapy in prostate cancer

NS Schmidt-Hegemann, C Zamboglou… - Radiotherapy and …, 2023 - Elsevier
Background and purpose There is no consensus concerning the appropriate use of
androgen deprivation therapy (ADT) during primary and postoperative external-beam …

Technological evolution of radiation treatment: Implications for clinical applications

R Pacelli, M Caroprese, G Palma, C Oliviero… - Seminars in …, 2019 - Elsevier
The contemporary approach to the management of a cancer patient requires an “ab initio”
involvement of different medical domains in order to correctly design an individual patient's …

De-escalation of therapy for prostate cancer

T Esen, B Esen, K Yamaoh, U Selek… - American Society of …, 2024 - ascopubs.org
Prostate cancer (PCa) is the second most commonly diagnosed cancer in men with around
1.4 million new cases every year. In patients with localized disease, management options …

FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?

KA Cengel, MM Kim, ES Diffenderfer… - Seminars in Radiation …, 2024 - Elsevier
FLASH is an emerging treatment paradigm in radiotherapy (RT) that utilizes ultra-high dose
rates (UHDR;> 40 Gy)/s) of radiation delivery. Developing advances in technology support …