ICU-Acquired Weakness and Recovery from Critical Illness | New England Journal of Medicine
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Prolonged immobility is harmful with rapid reductions in muscle mass, bone mineral density
and impairment in other body systems evident within the first week of bed rest which is …

Background: Increasing numbers of survivors of critical illness are at risk for physical,
cognitive, and/or mental health impairments that may persist for months or years after …

Delirium (acute confusion) complicates 15% to 50% of major operations in older adults and
is associated with other major postoperative complications, prolonged length of stay, poor …

Sepsis often is characterized by an acute brain dysfunction, which is associated with
increased morbidity and mortality. Its pathophysiology is highly complex, resulting from both …

Objective: Delirium duration is predictive of long-term cognitive impairment in intensive care
unit survivors. Hypothesizing that a neuroanatomical basis may exist for the relationship …

Objective: To compare and contrast the process used to implement an early mobility
program in ICUs at three different medical centers and to assess their impact on clinical …

In an invited editorial, I argue that critical care is facing a cross-roads. We can now save
many patients lives. But we need to broaden our sense of our mission to include …

ICU-acquired weakness (ICUAW) occurs with reported incidence rates from 25% to 100%.
Risk factors include immobility, sepsis, persistent systemic inflammation, multiorgan system …

Over the last 15 years the management of patients admitted in the ICU has changed
dramatically. A growing number of well designed randomized controlled studies have been …