In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA
polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and …

Yeast RNA polymerase II (Pol II) terminates transcription of coding transcripts through the
polyadenylation (pA) pathway and non-coding transcripts through the non-polyadenylation …

Transcriptome‐wide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …

The exosome and its nuclear specific subunit Rrp6 form a 3'-5'exonuclease complex that
regulates diverse aspects of RNA biology including 3'end processing and degradation of a …

Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable,
contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most …

Most functional eukaryotic mRNAs contain a 5′ 7-methylguanosine (m7G) cap. Although
capping is essential for many biological processes including mRNA processing, export and …

Long noncoding RNAs (lncRNAs) play important roles in the regulation of gene expression.
In fission yeast, glucose starvation triggers a transcriptional cascade of polyadenylated …

Multi-UTR genes are widely transcribed and express their alternative 3′ UTR isoforms in a
cell type-specific manner. As transcriptional enhancers regulate mRNA expression, we …

Transcriptional memory is critical for the faster reactivation of necessary genes upon
environmental changes and requires that the genes were previously in an active state …

Eukaryotic genomes are rich in transcription units encoding “long noncoding
RNAs”(lncRNAs). The purpose of all this transcription is unclear since most lncRNAs are …