[HTML][HTML] Similarity-based segmentation of multi-dimensional signals
The segmentation of time series and genomic data is a common problem in computational
biology. With increasingly complex measurement procedures individual data points are …
biology. With increasingly complex measurement procedures individual data points are …
Non-coding transcription by RNA polymerase II in yeast: Hasard or nécessité?
A Tudek, T Candelli, D Libri - Biochimie, 2015 - Elsevier
Recent developments of microarrays and deep sequencing techniques have unveiled an
unexpected complexity of the eukaryotic transcriptome, demonstrating that virtualy the entire …
unexpected complexity of the eukaryotic transcriptome, demonstrating that virtualy the entire …
NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics
In yeast, NuA3 histone acetyltransferase (NuA3 HAT) promotes acetylation of histone H3
lysine 14 (H3K14) and transcription of a subset of genes through interaction between the …
lysine 14 (H3K14) and transcription of a subset of genes through interaction between the …
[HTML][HTML] Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae
D Kyriakou, E Stavrou, P Demosthenous, G Angelidou… - BMC biology, 2016 - Springer
Background Transcriptome studies have revealed that many eukaryotic genomes are
pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However …
pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However …
[HTML][HTML] Coupling transcriptional state to large-scale repeat expansions in yeast
KA Shah, RJ McGinty, VI Egorova, SM Mirkin - Cell reports, 2014 - cell.com
Expansions of simple DNA repeats cause numerous hereditary disorders in humans.
Replication, repair, and transcription are implicated in the expansion process, but their …
Replication, repair, and transcription are implicated in the expansion process, but their …
Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal E site rRNA at the L1 stalk
AP Schuller, B Zinshteyn, SU Enam… - Nucleic acids …, 2018 - academic.oup.com
Upf1 is an SF1-family RNA helicase that is essential for the nonsense-mediated decay
(NMD) process in eukaryotes. While Upf1 has been shown to interact with 80S ribosomes …
(NMD) process in eukaryotes. While Upf1 has been shown to interact with 80S ribosomes …
RNA Pol II Assembly Affects ncRNA Expression
AI Garrido-Godino, I Gupta, V Pelechano… - International Journal of …, 2023 - mdpi.com
RNA pol II assembly occurs in the cytoplasm before translocation of the enzyme to the
nucleus. Affecting this assembly influences mRNA transcription in the nucleus and mRNA …
nucleus. Affecting this assembly influences mRNA transcription in the nucleus and mRNA …
A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation
Abstract The Nrd1–Nab3–Sen1 (NNS) complex integrates molecular cues to direct
termination of noncoding transcription in budding yeast. NNS is positively regulated by …
termination of noncoding transcription in budding yeast. NNS is positively regulated by …
Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome
U Szachnowski, S Andjus, D Foretek… - Life Science …, 2019 - life-science-alliance.org
Antisense long noncoding (aslnc) RNAs are extensively degraded by the nuclear exosome
and the cytoplasmic exoribonuclease Xrn1 in the budding yeast Saccharomyces cerevisiae …
and the cytoplasmic exoribonuclease Xrn1 in the budding yeast Saccharomyces cerevisiae …
Yeast RNA-binding protein Nab3 regulates genes involved in nitrogen metabolism
J Merran, JL Corden - Molecular and cellular biology, 2017 - Taylor & Francis
Termination of Saccharomyces cerevisiae RNA polymerase II (Pol II) transcripts occurs
through two alternative pathways. Termination of mRNAs is coupled to cleavage and …
through two alternative pathways. Termination of mRNAs is coupled to cleavage and …