Hierarchical functional system development supports executive function

AS Keller, VJ Sydnor, A Pines, DA Fair… - Trends in Cognitive …, 2023 - cell.com
In this perspective, we describe how developmental improvements in youth executive
function (EF) are supported by hierarchically organized maturational changes in functional …

Functional connectivity development along the sensorimotor-association axis enhances the cortical hierarchy

AC Luo, VJ Sydnor, A Pines, B Larsen… - Nature …, 2024 - nature.com
Human cortical maturation has been posited to be organized along the sensorimotor-
association axis, a hierarchical axis of brain organization that spans from unimodal …

Development of top-down cortical propagations in youth

A Pines, AS Keller, B Larsen, M Bertolero, A Ashourvan… - Neuron, 2023 - cell.com
Hierarchical processing requires activity propagating between higher-and lower-order
cortical areas. However, functional neuroimaging studies have chiefly quantified fluctuations …

[HTML][HTML] Omnipresence of the sensorimotor-association axis topography in the human connectome

KH Nenning, T Xu, AR Franco, KM Swallow, A Tambini… - NeuroImage, 2023 - Elsevier
Low-dimensional representations are increasingly used to study meaningful organizational
principles within the human brain. Most notably, the sensorimotor-association axis …

Age-related differences in resting-state functional connectivity from childhood to adolescence

AFP Sanders, MP Harms, S Kandala, S Marek… - Cerebral …, 2023 - academic.oup.com
The human brain is active at rest, and spontaneous fluctuations in functional MRI BOLD
signals reveal an intrinsic functional architecture. During childhood and adolescence …

[HTML][HTML] Cognitive flexibility across the lifespan: developmental differences in the neural basis of sustained and transient control processes during task switching

SA Schwarze, Y Fandakova, U Lindenberger - Current Opinion in …, 2024 - Elsevier
Highlights•Cognitive flexibility increases in childhood and declines in aging.•Transient
control underlying switch costs shows little change across the lifespan.•Sustained control …

[HTML][HTML] Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control

AC Parr, F Calabro, B Tervo-Clemmens… - Developmental …, 2022 - Elsevier
Inhibitory control can be less reliable in adolescence, however, in the presence of rewards,
adolescents' performance often improves to adult levels. Dopamine is known to play a role …

Atypical functional connectivity hierarchy in Rolandic epilepsy

Q Zhang, J Li, Y He, F Yang, Q Xu, S Larivière… - Communications …, 2023 - nature.com
Functional connectivity hierarchy is an important principle in the process of brain functional
organization and an important feature reflecting brain development. However, atypical brain …

In vivo whole-cortex marker of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth

S Zhang, B Larsen, VJ Sydnor, T Zeng… - Proceedings of the …, 2024 - National Acad Sciences
A balanced excitation-inhibition ratio (E/I ratio) is critical for healthy brain function. Normative
development of cortex-wide E/I ratio remains unknown. Here, we noninvasively estimate a …

[HTML][HTML] If the doors of perception were cleansed, would chronic pain be relieved? Evaluating the benefits and risks of psychedelics

RH Dworkin, BT Anderson, N Andrews, RR Edwards… - The Journal of …, 2022 - Elsevier
Psychedelic substances have played important roles in diverse cultures, and ingesting
various plant preparations to evoke altered states of consciousness has been described …