Cytokine and cytokine receptor gene polymorphisms and their functionality

AJP Smith, SE Humphries - Cytokine & growth factor reviews, 2009 - Elsevier
Cytokines, signaling proteins produced by a variety of cell types, are essential for the
development and functioning of both innate and adaptive immune response. Cytokine gene …

Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention

A Badawi, A Klip, P Haddad, DEC Cole… - … syndrome and obesity …, 2010 - Taylor & Francis
Obesity is a major risk factor for type 2 diabetes mellitus (T2DM), which is a significant health
problem worldwide. Active disease is associated with low-grade chronic inflammation …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Relationships between disease activity and serum and fecal biomarkers in patients with Crohn's disease

J Jones, EV Loftus Jr, R Panaccione, LS Chen… - Clinical …, 2008 - Elsevier
BACKGROUND & AIMS: The quantitative relationships between instruments and assays that
measure clinical, endoscopic, and biologic disease activity in patients with Crohn's disease …

Association of Common Polymorphisms in Inflammatory Genes Interleukin (IL)6, IL8, Tumor Necrosis Factor α, NFKB1, and Peroxisome Proliferator-activated …

S Landi, V Moreno, L Gioia-Patricola, E Guino… - Cancer research, 2003 - AACR
Animal models and epidemiological observations suggest that a continuous inflammatory
condition predisposes to colorectal cancer (CRC), but the roles of different elements …

Cytokine gene polymorphism in human disease: on-line databases, Supplement 3

MV Hollegaard, JL Bidwell - Genes & Immunity, 2006 - nature.com
Within the past few years, the focus on cytokine single nucleotide polymorphism (SNP)
function and association with human diseases has increased considerably. This third …

Interleukin-1β and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis

MC Camargo, R Mera, P Correa, RM Peek Jr… - … Biomarkers & Prevention, 2006 - AACR
Background: Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN)
genes have been inconsistently associated with gastric cancer risk. We examined these …

[HTML][HTML] Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

S De Iudicibus, R Franca, S Martelossi… - World journal of …, 2011 - ncbi.nlm.nih.gov
Natural and synthetic glucocorticoids (GCs) are widely employed in a number of
inflammatory, autoimmune and neoplastic diseases, and, despite the introduction of novel …

[PDF][PDF] HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination

C Wang, J Tang, W Song, E Lobashevsky… - …, 2004 - Wiley Online Library
Variable immune responses to hepatitis B virus (HBV) infection and recombinant HBV
vaccines have been associated with polymorphisms in several genes within the human …

[HTML][HTML] The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what …

G Morris, BK Puri, RE Frye - Metabolic brain disease, 2017 - Springer
The conceptualisation of autistic spectrum disorder and Alzheimer's disease has undergone
something of a paradigm shift in recent years and rather than being viewed as single …