Drug-induced hepatitis remains a challenging problem for drug development and safety
because of the lack of animal models. In the current work, we discovered a unique …

Background: Genetic polymorphisms of cytokines have been associated with the
susceptibility, severity, and clinical outcome of inflammatory diseases, such as periodontitis …

Abstract Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive
and anti-angiogenic functions and may have both tumour-promoting and-inhibiting …

Evidence from epidemiological and experimental studies has shown that non-steroidal anti-
inflammatory drugs (NSAIDs) reduce the risk of colorectal cancer (CRC). The function of …

Cytokines have an important role in the pathogenesis and disease progression of oral lichen
planus (OLP). The aim of this study was to investigate the impact of gene polymorphisms of …

Schizophrenia and affective psychoses are severe and prevalent psychiatric disorders
described in all cultures and populations. Whether these functional psychoses are two …

OBJECTIVES Host genetic factors, including the IL1 gene cluster, play a key role in
determining the long-term outcome of Helicobacter pylori infection. The aim of the study was …

Preeclampsia (PE) is one of the most serious disorders of human pregnancy and Th1/Th2
imbalance may play a role in its etiology. Considering that cytokine production is under …

Abstract Lack of Association between Cytokine Gene Polymorphisms and Silicosis and
Pulmonary Tuberculosis in Chinese Iron Miners: Fen Wu, et al. Department of Occupational …

Suspicion that host genetic factors determine variability in the course of natural HIV-1
infection deepened throughout the 1980s and early 1990s [1, 2], but only relatively recently …