Numerous studies have provided support for genetic susceptibility to tuberculosis (TB);
however, heterogeneity in disease expression has hampered previous genetic studies. The …

Tumor necrosis factor (TNF) is critical to regulation of inflammation. Genetic variation in the
promoter region of TNF has been associated with expression differences, and a range of …

Several genes encoding for different cytokines may play crucial roles in host susceptibility to
Brucellosis, since the cytokine production capacity varies among individuals and depends …

Introduction 3. Pathogenesis of perinatal brain injury 3.1. Intraventricular hemorrhage 3.2.
Periventricular leukomalacia 3.3. Role of inflammation in perinatal brain injury 3.3. 1. Animal …

Background Cytokines are key regulators of measles vaccine humoral and cellular
immunity. Single-nucleotide polymorphisms (SNPs) that are associated with differences in …

Background To investigate whether Chinese non–small-cell lung cancer (NSCLC) patients
with risk of radiation pneumonitis (RP)(grade≥ 3) caused by radiotherapy display reliable …

Abstract In West Bengal, India, at present, more than 26 million people are exposed to
arsenic through drinking water. Among them, only 15–20% manifest arsenic-induced …

Activation of macrophages and their antimicrobial activities by interferon-gamma (IFN-γ)
plays a crucial role in controlling Brucella infection. Interleukin-4 (IL-4) antagonizes the …

Purpose.: Noninfectious uveitis is a sight-threatening immune-mediated intraocular
inflammatory disorder. The inheritance of uveitis in multiplex families and its association with …

Antigen presentation and immune activation are essential to the effective control of
infectious diseases. In 485 North American adolescents at high risk for genital Chlamydia …