The ability to efficiently scavenge nutrients in the host is essential for the viability of any
pathogen. All catabolic pathways must begin with the transport of substrate from the …

Chemotherapy for tuberculosis (TB) is lengthy and could benefit from synergistic adjuvant
therapeutics that enhance current and novel drug regimens. To identify genetic determinants …

Among bioactive peptides, cationic antimicrobial peptides (AMPs), also referred to as host
defence peptides (HDPs), are valuable tools to treat infections, being able to kill a wide …

In our previous study, several iron-related outer membrane proteins in Aeromonas
hydrophila, a serious pathogen of farmed fish, conferred high immunoprotectivity to fish, and …

Iron is essential for DNA synthesis, respiration, energy metabolism, and key metabolic
reactions intrinsic to life because of its capability to accept and release electrons easily and …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, poses a great threat
to human health. With the emergence of drug resistant Mtb strains, new therapeutics are …

Zinc is an essential nutrient in biological systems due to its structural or catalytic requirement
in proteins involved in diverse cellular processes. To meet this cellular demand, microbes …

Background: New strategies are needed to combat multidrug-resistant bacteria. The
restriction of iron uptake by bacteria is a promising way to inhibit their growth. We aimed to …

The present study investigated the effects of iron, iron chelators, and mutations of tonB or
iroN fepA genes on the growth and virulence of Salmonella Typhimurium. Results indicated …

Marine snow is an important habitat for microbes, characterized by chemical and physical
properties contrasting those of the ambient water. The higher nutrient concentrations in …