Systematic review with meta‐analysis: the prevalence of anxiety and depression in patients with irritable bowel syndrome

M Zamani, S Alizadeh‐Tabari… - Alimentary pharmacology …, 2019 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a common and potential disabling functional
gastrointestinal disorder. Studies have revealed a possible association between IBS and …

[HTML][HTML] The role of visceral hypersensitivity in irritable bowel syndrome: pharmacological targets and novel treatments

MH Farzaei, R Bahramsoltani, M Abdollahi… - Journal of …, 2016 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists
and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral …

A systematic review of the economic and humanistic burden of illness in irritable bowel syndrome and chronic constipation

D Nellesen, K Yee, A Chawla, BE Lewis… - Journal of managed care …, 2013 - jmcp.org
BACKGROUND: Irritable bowel syndrome (IBS) and chronic constipation (CC) are common
functional gastrointestinal disorders affecting 14% and 20% of the US population …

[HTML][HTML] The mycobiome in health and disease: emerging concepts, methodologies and challenges

PY Tiew, M Mac Aogain, NABM Ali, KX Thng, K Goh… - Mycopathologia, 2020 - Springer
Fungal disease is an increasingly recognised global clinical challenge associated with high
mortality. Early diagnosis of fungal infection remains problematic due to the poor sensitivity …

Psychological comorbidity in gastrointestinal diseases: Update on the brain-gut-microbiome axis

H Person, L Keefer - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
The high comorbidity of psychological disorders in both functional and organic
gastrointestinal diseases suggests the intimate and complex link between the brain and the …

[HTML][HTML] Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities

RD Moloney, SM O'Mahony, TG Dinan… - Frontiers in …, 2015 - frontiersin.org
Visceral pain is a global term used to describe pain originating from the internal organs,
which is distinct from somatic pain. It is a hallmark of functional gastrointestinal disorders …

[HTML][HTML] Bifidobacterium longum and Lactobacillus helveticus synergistically suppress stress-related visceral hypersensitivity through hypothalamic-pituitary-adrenal …

A Ait-Belgnaoui, I Payard, C Rolland… - Journal of …, 2018 - ncbi.nlm.nih.gov
Methods After a 2-week treatment with a combined probiotic formulation, or L. helveticus or
B. longum alone in stressed mice, the visceral pain in response to CRD was recorded. The …

[HTML][HTML] The potential role of gut mycobiome in irritable bowel syndrome

Y Gu, G Zhou, X Qin, S Huang, B Wang… - Frontiers in …, 2019 - frontiersin.org
The human gut is inhabited by diverse microorganisms that play crucial roles in health and
disease. Gut microbiota dysbiosis is increasingly considered as a vital factor in the …

Stress and visceral pain: from animal models to clinical therapies

M Larauche, A Mulak, Y Taché - Experimental neurology, 2012 - Elsevier
Epidemiological studies have implicated stress (psychosocial and physical) as a trigger of
first onset or exacerbation of irritable bowel syndrome (IBS) symptoms of which visceral pain …

Altered neuro-endocrine–immune pathways in the irritable bowel syndrome: the top-down and the bottom-up model

C Stasi, M Rosselli, M Bellini, G Laffi… - Journal of gastroenterology, 2012 - Springer
The interaction between the brain and the gut as a pathological mechanism of functional
gastrointestinal disorders has been recently recognized in the pathophysiology of the …