The process of aging refers to physiological changes that occur to an organism as time
progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the …

Aging is accompanied by a progressive loss of skeletal muscle mass and strength. The
mechanisms underlying this phenomenon are certainly multifactorial and still remain to be …

Nicotinamide adenine dinucleotide (NAD) can be used as an initiating nucleotide in RNA
transcription to produce NAD-capped RNA (NAD-RNA). RNA modification by NAD that links …

Aging and cancer are increasingly becoming big challenges for public health worldwide due
to increased human life expectancy. Meanwhile, aging is one of the major risk factors for …

Simple Summary Metastasis is the main cause of poor outcomes in ovarian cancer and
metastasis-initiating cells are a subpopulation of cancer cells that can effectively establish …

In recent years, the impact of methylation modifications on Dickkopf-1 (DKK1) in relation to
ankylosing spondylitis (AS) has remained elusive. Our objective was to investigate the …

Osteoporosis is an age-related, systemic skeletal disease that poses a significant public
health challenge in contemporary society. Development at the epigenetic level is emerging …

Diminished ovarian reserve can be regarded as a sentinel indicator to foreshadow severe
follicular loss and, ultimately, systemic aging. The negative slope of human ovulatory fidelity …

The epigenome is a dynamic system of chemical modifications that operate to control
chromatin structure and regulate gene activity without altering the underlying DNA …

Parkinson's disease (PD) is one of the most common neurodegenerative diseases.
Multiplication of SNCA, a gene encoding synaptic protein alpha-synuclein, leads to PD in a …