The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

Integration of heterogeneous and high-dimensional data (eg, multiomics) is becoming
increasingly important. Existing multimodal classification algorithms mainly focus on …

Current treatments for Alzheimer's disease (AD) that focus on inhibition of Aβ aggregation
failed to show effectiveness in people who already had Alzheimer's symptoms. Strategies …

With the rapid development of various data acquisition technologies, more and more
multimodal data come into being. It is important to integrate different modalities which are …

Alzheimer's disease (AD), the most common form of dementia, is a progressive and
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …

Background Delaying the transition from minimal cognitive impairment to Alzheimer's
dementia is a major concern in Alzheimer's disease (AD) therapeutics. Pathological signs of …

Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …

Amyloid‐β (Aβ) toxicity is considered to be companioned by Tau phosphorylation in
Alzheimer's disease (AD). The clinical AD therapy is usually subjected to low blood‐brain …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …