Proliferating cell nuclear antigen (PCNA) protein is one of the central molecules responsible
for decisions of life and death of the cell. The PCNA gene is induced by p53, while PCNA …

Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the
lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they …

Human biomonitoring of early genetic effects requires accurate, sensitive and, if possible,
easy and not too time-consuming methodologies to assess mutations. One of the most …

Cohen and thermal processes occur roughly a million times per day in each of the trillions of
cells in our bodies, but only about one per cell per day remains unrepaired and survives as …

Numerous investigators have reported that irradiation of cells with a low dose of ionizing
radiation (IR) can induce a condition of enhanced radioresistance, ie a radioadaptive …

An ultrasensitive assay for measuring DNA base damage is described that couples
immunochemical recognition with capillary electrophoresis and laser-induced fluorescence …

A long-held central dogma of radiation biology has been that the carcinogenic effects of
ionizing radiation (IR) are induced by the direct and radiolytic actions of IR on nuclear DNA …

Biological tissues operate through cells that act together within signaling networks. These
assure coordinated cell function in the face of constant exposure to an array of potentially …

Abstract Redpath, JL, Liang, D., Taylor, TH, Christie, C. and Elmore, E. The Shape of the
Dose–Response Curve for Radiation-Induced Neoplastic Transformation In Vitro: Evidence …

Abstract Iyer, R. and Lehnert, BE Alpha-Particle-Induced Increases in the Radioresistance of
Normal Human Bystander Cells. Radiat. Res. 157, 3–7 (2002). Numerous investigators have …