[HTML][HTML] Lipid metabolism and cancer
Dysregulation in lipid metabolism is among the most prominent metabolic alterations in
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …
The metabolic nature of inflammatory bowel diseases
TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022 - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
We report a genome-wide association study (GWAS) of coronary artery disease (CAD)
incorporating nearly a quarter of a million cases, in which existing studies are integrated with …
incorporating nearly a quarter of a million cases, in which existing studies are integrated with …
Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …
HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …
preclinical, and clinical trial results, provide strong support for a causal association between …
[HTML][HTML] SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids
Summary Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can be …
syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can be …
Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice
L Ma, Y Ni, Z Wang, W Tu, L Ni, F Zhuge, A Zheng… - Gut …, 2020 - Taylor & Francis
Obesity is associated with impaired intestinal barrier function and dysbiosis of the gut
microbiota. Spermidine, a polyamine that acts as an autophagy inducer, has important …
microbiota. Spermidine, a polyamine that acts as an autophagy inducer, has important …
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …
are complex and can be unique to each individual. We performed deep metagenomic …
The role of gut microbiota on cholesterol metabolism in atherosclerosis
M Vourakis, G Mayer, G Rousseau - International Journal of Molecular …, 2021 - mdpi.com
Hypercholesterolemia plays a causal role in the development of atherosclerosis and is one
of the main risk factors for cardiovascular disease (CVD), the leading cause of death …
of the main risk factors for cardiovascular disease (CVD), the leading cause of death …
[HTML][HTML] An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism
The mechanisms by which the early-life microbiota protects against environmental factors
that promote childhood obesity remain largely unknown. Using a mouse model in which …
that promote childhood obesity remain largely unknown. Using a mouse model in which …
Gut microbial fatty acid isomerization modulates intraepithelial T cells
The human gut microbiome constantly converts natural products derived from the host and
diet into numerous bioactive metabolites,–. Dietary fats are essential micronutrients that …
diet into numerous bioactive metabolites,–. Dietary fats are essential micronutrients that …