CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef
T Ueno, C Motozono, S Dohki, P Mwimanzi… - The Journal of …, 2008 - journals.aai.org
HIV-1 Nef plays multiple roles in modulating immune responses, even though it is a
dominant CTL target itself. How Nef accomplishes the balance between such conflicting …
dominant CTL target itself. How Nef accomplishes the balance between such conflicting …
Exosomes are unlikely involved in intercellular Nef transfer
HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Several recent
studies including ours have demonstrated that Nef can be transferred to neighboring cells …
studies including ours have demonstrated that Nef can be transferred to neighboring cells …
HIV-1 Nef in macrophage-mediated disease pathogenesis
Combined anti-retroviral therapy (cART) has significantly reduced the number of AIDS-
associated illnesses and changed the course of HIV-1 disease in developed countries …
associated illnesses and changed the course of HIV-1 disease in developed countries …
Mechanisms of human immunodeficiency virus-associated lymphocyte regulated cell death
AC Paim, AD Badley, NW Cummins - AIDS Research and Human …, 2020 - liebertpub.com
Human immunodeficiency virus-1 (HIV-1) causes CD4 T cell depletion through a number of
mechanisms, including programmed cell death pathways (both apoptotic and nonapoptotic) …
mechanisms, including programmed cell death pathways (both apoptotic and nonapoptotic) …
Conformational transition of membrane-associated terminally acylated HIV-1 Nef
B Akgun, S Satija, H Nanda, GF Pirrone, X Shi… - Structure, 2013 - cell.com
Many proteins are posttranslationally modified by acylation targeting them to lipid
membranes. While methods such as X-ray crystallography and nuclear magnetic resonance …
membranes. While methods such as X-ray crystallography and nuclear magnetic resonance …
A negative correlation between hsa-miR29a-3p level and HIV-1 viral load in human serum; potentiate criteria for patients screening
M karkhaneh Mahmoudi, A Letafati, BM Soltani… - Microbial …, 2023 - Elsevier
Abstract Human Immunodeficiency Virus type-1 (HIV-1) causes persistent and life-
threatening infection, leading to progressive disease. MicroRNAs (miRNAs) are regulators of …
threatening infection, leading to progressive disease. MicroRNAs (miRNAs) are regulators of …
HIV-1 and drug abuse comorbidity: Lessons learned from the animal models of NeuroHIV
Various research studies that have investigated the association between HIV infection and
addiction underpin the role of various drugs of abuse in impairing immunological and non …
addiction underpin the role of various drugs of abuse in impairing immunological and non …
HIV-1 Nef expression in microglia disrupts dopaminergic and immune functions with associated mania-like behaviors
S Acharjee, WG Branton, P Vivithanaporn… - Brain, behavior, and …, 2014 - Elsevier
Background Neuropsychiatric disorders during HIV/AIDS are common although the
contribution of HIV-1 infection within the brain, and in particular individual HIV-1 proteins, to …
contribution of HIV-1 infection within the brain, and in particular individual HIV-1 proteins, to …
Macrophage targeted nanocarrier delivery systems in HIV therapeutics
Introduction Human immunodeficiency virus (HIV) targets and modulates the immune
system increasing the risk of other associated infections. Highly active antiretroviral therapy …
system increasing the risk of other associated infections. Highly active antiretroviral therapy …
HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway
A Chaudhry, DA Verghese, SR Das… - The Journal of …, 2009 - journals.aai.org
HIV-1 Nef has been reported to disrupt MHC class II (MHCII)-mediated Ag presentation by a
dual strategy that comprises a reduction in cell surface levels of peptide-loaded mature …
dual strategy that comprises a reduction in cell surface levels of peptide-loaded mature …