Antidepressant effects of the traditional Chinese herbal formula Xiao-Yao-San and its bioactive ingredients

YT Wang, XL Wang, ZZ Wang, L Lei, D Hu, Y Zhang - Phytomedicine, 2023 - Elsevier
Background Depression is one of the most debilitating and severe psychiatric disorders and
a serious public health concern. Currently, many treatments are indicated for depression …

[HTML][HTML] Research progress on classical traditional Chinese medicine formula xiaoyaosan in the treatment of depression

J Chen, C Lei, X Li, Q Wu, C Liu, Q Ma… - Frontiers in …, 2022 - frontiersin.org
Depression is an emotional disorder that is problematic in psychiatry owing to its unclear
etiology and unknown pathogenesis. Traditional Chinese medicine formulations such as …

[HTML][HTML] Proprietary Medicines Containing Bupleurum chinense DC. (Chaihu) for Depression: Network Meta-Analysis and Network Pharmacology Prediction

Q Li, W Lu, Q Zhang, Y Zhao, C Wu… - Frontiers in …, 2022 - frontiersin.org
Background and Aims: The rapid development of society has resulted in great competitive
pressures, leading to the increase in suicide rates as well as incidence and recurrence of …

Jiawei-Xiaoyao pill elicits a rapid antidepressant effect, dependent on activating CaMKII/mTOR/BDNF signaling pathway in the hippocampus

H Zhang, Y Sun, Z Huang, Z Wu, Y Ying, R Liu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Jiawei-Xiaoyao pill (JWX), a traditional Chinese
medicine, was recorded in ancient Chinese medicine pharmacopoeia using for treatment of …

[HTML][HTML] Clinical efficacy and safety of traditional Chinese medicine Xiao Yao San in insomnia combined with anxiety

J Hu, J Teng, W Wang, N Yang, H Tian, W Zhang… - Medicine, 2021 - journals.lww.com
Background: Patients with long-term insomnia generally experience anxiety and depression.
Traditional sleeping pills and anti-anxiety drugs have certain limitations. Xiao Yao San …

[HTML][HTML] A network pharmacology and molecular docking approach to reveal the mechanism of Chaihu Anxin Capsule in depression

L Yang, Y Zhao, R Qu, Y Fu, C Zhou… - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction As one of the most frequently diagnosed mental disorders, depression is
expected to become the most common disease worldwide by 2030. Previous studies have …

[HTML][HTML] Xiaoyao Pills, a Chinese patent medicine, treats mild and moderate depression: a randomized clinical trial combined with DNA methylation analysis

L Fan, P Zeng, X Wang, X Mo, Q Ma, X Zhou, N Yuan… - Phytomedicine, 2024 - Elsevier
Background Xiaoyao pills (XYP) is a commercial Chinese patent medicine used in the
treatment of depression. However, the mechanisms underlying its therapeutic effects, as well …

Effects of Chinese herbal medicines on dementia risk in patients with sleep disorders in Taiwan

CJ Chen, X Liu, JS Chiou, LW Hang, TM Li… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Sleep disorders affect an estimated 150 million people
worldwide and result in adverse health, safety, and work performance-related outcomes that …

Studying CNS effects of Traditional Chinese Medicine using zebrafish models

D Wang, G Hu, J Wang, D Yan, M Wang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Although Traditional Chinese Medicine (TCM)
has a millennia-long history of treating human brain disorders, its complex multi-target …

Separation and purification of magnoflorine, spinosin, and 6‴‐feruloyspinosin from Ziziphi Spinosae Semen by high‐speed counter‐current chromatography

H Xu, Y Niu, Y Sun, M Xia, D Lin… - Journal of separation …, 2021 - Wiley Online Library
In the study, high‐speed counter‐current chromatography was used for separation and
purification of magnoflorine, spinosin, and 6‴‐feruloyspinosin from Ziziphi Spinosae …