Adhesive mixtures for inhalation are the most widely used type of formulation in dry powder
inhalation products. Although they have been the subject of active research, the …

Blending drug and carrier powders to produce homogeneous drug–carrier adhesive
mixtures is a key step in the production of dry powder inhaler (DPI) formulations. Although …

Purpose Accurate and consistent delivery of materials by well-designed feeders ensures
overall process stability. Importantly, feeding performance is strongly dependent on material …

Abstract Poly-L-lysine (PLL) is a promising candidate for the treatment of pulmonary
infection with lower occurrence of drug-resistance due to its unique antibacterial …

Swellable microparticles (SMs) provide a potential strategy for achieving sustained
inhalation therapy. However, spray dried SMs are highly hygroscopic, exhibiting poor …

Positron Emission Particle Tracking (PEPT) is a technique which allows the three-
dimensional, internal dynamics of opaque systems to be imaged with high temporal and …

Abstract D-Limonene (D-Lim), a volatile oil extracted from citrus fruits, has therapeutic effects
on lung inflammation and cancer, whilst the deep delivery of D-Lim was challenging due to …

Many efforts have been made in the past to understand the function of lactose fines which
are given as a ternary component to carrier-based dry powder inhaler formulations. It is …

Pulmonary drug delivery has gained great attention in local or systemic diseases therapy,
however it is still difficult to scale-up DPI production due to the complexity of interactions …

The effect of milled and micronized lactose fines on the fluidization and in vitro
aerosolization properties of dry powder inhaler (DPI) formulations was investigated, and the …