Unlocking novel therapies: Cyclic peptide design for amyloidogenic targets through synergies of experiments, simulations, and machine learning
D de Raffele, IM Ilie - Chemical Communications, 2024 - pubs.rsc.org
Existing therapies for neurodegenerative diseases like Parkinson's and Alzheimer's address
only their symptoms and do not prevent disease onset. Common therapeutic agents, such as …
only their symptoms and do not prevent disease onset. Common therapeutic agents, such as …
Characterizing fibril morphological changes by spirooxindoles for neurodegenerative disease application
Fibrillation of proteins and polypeptides, which leads to the deposition of plaques in cells
and tissues has been widely associated with many neuropathological diseases. Inhibition of …
and tissues has been widely associated with many neuropathological diseases. Inhibition of …
Converting short-acting insulin into thermo-stable longer-acting insulin using multi-layer detachable microneedles
T Phoka, N Wanichwecharungruang… - Journal of …, 2024 - Elsevier
The detachable dissolving microneedles (DDMNs) feature an array of needles capable of
being separated from the base sheet during administration. Here they were fabricated to …
being separated from the base sheet during administration. Here they were fabricated to …
Green synthesis of silver nanoparticles using aqueous extract of Aloysia citrodora leaves and investigation of antioxidant, anti- amyloid and anti-cancer properties
Aloysia citrodora is very important in Iranian traditional medicine. The aim of this study was
to produce silver nanoparticles with aqueous extract of A. citrodora and investigate its …
to produce silver nanoparticles with aqueous extract of A. citrodora and investigate its …