Challenges in liver cancer and possible treatment approaches

D Anwanwan, SK Singh, S Singh, V Saikam… - Biochimica et Biophysica …, 2020 - Elsevier
Globally, liver cancer is the most frequent fatal malignancy; in the United States, it ranks fifth.
Patients are often diagnosed with liver cancer in advanced stages, contributing to its poor …

[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer

MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …

[HTML][HTML] A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties

S Liu, Y Sun, Y Hou, L Yang, X Wan, Y Qin… - Journal of hematology & …, 2021 - Springer
Abstract Background Cancer stem cells (CSCs) are considered as the major cause to tumor
initiation, recurrence, metastasis, and drug resistance, driving poor clinical outcomes in …

[HTML][HTML] CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization …

XL Ma, MN Shen, B Hu, BL Wang, WJ Yang… - Journal of hematology & …, 2019 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies
worldwide because of rapid progression and high incidence of metastasis or recurrence …

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

J Chen, J Zhang, Y Gao, Y Li, C Feng… - Nucleic acids …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been proven to play important roles in
transcriptional processes and various biological functions. Establishing a comprehensive …

LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR‐128/CD151 pathway in hepatocellular carcinoma

PF Zhang, F Wang, J Wu, Y Wu… - Journal of cellular …, 2019 - Wiley Online Library
Dysregulation of long noncoding RNAs (lncRNAs) plays important roles in carcinogenesis
and tumor progression, including hepatocellular carcinoma (HCC). Small nucleolar RNA …

[HTML][HTML] Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a

X Xin, M Wu, Q Meng, C Wang, Y Lu, Y Yang, X Li… - Molecular Cancer, 2018 - Springer
Abstract Background Long noncoding RNA HULC is highly up-regulation in human
hepatocellular carcinoma (HCC). However, the functions of HULC in hepatocarcinogenesis …

LncRNA CDKN2B-AS1 promotes tumor growth and metastasis of human hepatocellular carcinoma by targeting let-7c-5p/NAP1L1 axis

Y Huang, B Xiang, Y Liu, Y Wang, H Kan - Cancer letters, 2018 - Elsevier
Long non-coding RNAs (lncRNAs) show great potential as therapeutic targets in many
diseases including hepatocellular carcinoma (HCC). Here, we aimed to investigate the …

NcPath: A novel platform for visualization and enrichment analysis of human non-coding RNA and KEGG signaling pathways

Z Li, Y Zhang, J Fang, Z Xu, H Zhang, M Mao… - …, 2023 - academic.oup.com
Non-coding RNAs play important roles in transcriptional processes and participate in the
regulation of various biological functions, in particular miRNAs and lncRNAs. Despite their …

LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma

L Peng, Y Chen, Q Ou, X Wang, N Tang - International …, 2020 - Elsevier
Long non-coding RNA (lncRNA) is a kind of important molecules involved in the formation of
immune landscape in tumor microenvironment. However, there are few studies on the …