Recent molecularly targeted approach gains advance in breast cancer treatment. However,
the estimated 5-year survival rate has not met the desired expectation for improvement …

Cell cycle is regulated by a number of proteins namely cyclin-dependent kinases (CDKs)
and their associated cyclins which bind with and activate CDKs in a phase specific manner …

Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …

The long non-coding RNA, plasmacytoma variant translocation 1 (PVT1), is highly
expressed in a variety of tumors, and is believed to be a potential oncogene. However, the …

Background/Aims: Circular RNAs (circRNAs) are key regulators in the development and
progression of human cancers, however its role in non-small cell lung cancer (NSCLC) …

Cancer cells usually utilize glucose as a carbon source for aerobic glycolysis, a
phenomenon known as the Warburg effect. Increasing studies have shown that PVT1 (a …

Favorable clinical evidence suggests that the next trend in new treatments for advanced non-
small cell lung cancer (NSCLC) will be combination therapies. However, inevitable …

Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than
200 nucleotides that are involved in the development and progression of many types of …