LncRNAs in non-small-cell lung cancer

L Ginn, L Shi, M La Montagna, M Garofalo - Non-coding RNA, 2020 - mdpi.com
Lung cancer is associated with a high mortality, with around 1.8 million deaths worldwide in
2018. Non-small-cell lung cancer (NSCLC) accounts for around 85% of cases and, despite …

Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression

Z Chen, X Chen, B Lu, Y Gu, Q Chen, T Lei… - Journal of hematology & …, 2020 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) are known to regulate tumorigenesis
and cancer progression, but their contributions to non-small-cell lung cancer (NSCLC) …

[HTML][HTML] Exploration of serum exosomal LncRNA TBILA and AGAP2-AS1 as promising biomarkers for diagnosis of non-small cell lung cancer

Y Tao, Y Tang, Z Yang, F Wu, L Wang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Non-small cell lung cancer is the most common type of cancer with a poor prognosis, and
development of an effective diagnostic method is urgently needed. Exosomal lncRNAs, a …

Estrogen receptor β promotes the vasculogenic mimicry (VM) and cell invasion via altering the lncRNA-MALAT1/miR-145-5p/NEDD9 signals in lung cancer

W Yu, J Ding, M He, Y Chen, R Wang, Z Han, EZ Xing… - Oncogene, 2019 - nature.com
While estrogen receptor β (ERβ) may impact the progression of non-small cell lung cancer
(NSCLC), its linkage to alteration of the vasculogenic mimicry (VM) formation to influence the …

PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities

MA Hakami, A Hazazi, FR Khan, O Abdulaziz… - … -Research and Practice, 2023 - Elsevier
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …

Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128

F He, Z Song, H Chen, Z Chen, P Yang, W Li, Z Yang… - Oncogene, 2019 - nature.com
Long noncoding RNAs (lncRNAs) are implicated in human cancer, but their mechanisms of
action are largely unknown. In this study, we investigated lncRNA alterations that contribute …

YAP and TAZ in lung cancer: oncogenic role and clinical targeting

F Lo Sardo, S Strano, G Blandino - Cancers, 2018 - mdpi.com
Lung cancer is the leading cause of cancer death in the world and there is no current
treatment able to efficiently treat the disease as the tumor is often diagnosed at an advanced …

LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

QQ Chang, CY Chen, Z Chen, S Chang - Radiology and Oncology, 2019 - sciendo.com
Background. Cervical cancer is one of the most frequent malignancies among females
worldwide. Increasing evidence have indicated the participation of long noncoding RNAs …

[HTML][HTML] Knockdown of Lncrna PVT1 enhances radiosensitivity in non-small cell lung cancer by sponging Mir-195

D Wu, Y Li, H Zhang, X Hu - Cellular Physiology and Biochemistry, 2017 - karger.com
Background/Aims: Plasmacytoma variant translocation 1 (PVT1) exerts an oncogenic role in
many tumors, including lung cancer. However, the roles of PVT1 in regulating …

Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease

D Traversa, G Simonetti, D Tolomeo, G Visci… - British journal of …, 2022 - nature.com
The plasmacytoma variant translocation 1 (PVT1) is a long non-coding RNA gene involved
in human disease, mainly in cancer onset/progression. Although widely analysed, its …