Infectious keratitis: A review

M Cabrera‐Aguas, P Khoo… - Clinical & Experimental …, 2022 - Wiley Online Library
Globally, infectious keratitis is the fifth leading cause of blindness. The main predisposing
factors include contact lens wear, ocular injury and ocular surface disease. Staphylococcus …

[HTML][HTML] The use of in vivo confocal microscopy in fungal keratitis–Progress and challenges

IM Bakken, CJ Jackson, TP Utheim, E Villani… - The ocular …, 2022 - Elsevier
Fungal keratitis (FK) is a serious and sight-threatening corneal infection with global reach.
The need for prompt diagnosis is paramount, as a delay in initiation of treatment could lead …

[HTML][HTML] The orphan drug for acanthamoeba keratitis (ODAK) trial: PHMB 0.08%(polihexanide) and placebo versus PHMB 0.02% and propamidine 0.1%

JKG Dart, V Papa, P Rama, KA Knutsson, S Ahmad… - Ophthalmology, 2024 - Elsevier
Purpose To compare topical PHMB (polihexanide) 0.02%(0.2 mg/ml)+ propamidine 0.1%(1
mg/ml) with PHMB 0.08%(0.8 mg/ml)+ placebo (PHMB 0.08%) for Acanthamoeba keratitis …

[HTML][HTML] Diagnosis of Acanthamoeba Keratitis: Past, Present and Future

M Azzopardi, YJ Chong, B Ng, A Recchioni… - Diagnostics, 2023 - mdpi.com
Acanthamoeba keratitis (AK) is a painful and sight-threatening parasitic corneal infection. In
recent years, the incidence of AK has increased. Timely and accurate diagnosis is crucial …

[HTML][HTML] Diagnosis of fungal keratitis in low-income countries: evaluation of smear microscopy, culture, and in vivo confocal microscopy in Nepal

JJ Hoffman, R Yadav, SD Sanyam, P Chaudhary… - Journal of Fungi, 2022 - mdpi.com
Clinically diagnosing fungal keratitis (FK) is challenging; diagnosis can be assisted by
investigations including in vivo confocal microscopy (IVCM), smear microscopy, and culture …

[HTML][HTML] Differentiation of acanthamoeba keratitis from other non-acanthamoeba keratitis: risk factors and clinical features

SO Alreshidi, JM Vargas, K Ahmad, AY Alothman… - Plos one, 2024 - journals.plos.org
Introduction Infectious Keratitis is one of the most common ocular emergencies seen by
ophthalmologists. Our aim is to identify the risk factors and clinical features of …

Utility of investigation for suspected microbial keratitis: a diagnostic accuracy study

S Tuft, C Bunce, S De, J Thomas - Eye, 2023 - nature.com
Purpose The true disease status of a population with suspected microbial keratitis (MK)
cannot be verified. There is not an accurate (gold) reference standard to confirm infection …

[HTML][HTML] Analysis of microbial keratitis incidence, isolates and in-vitro antimicrobial susceptibility in the East of England: a 6-year study

M Moledina, HW Roberts, A Mukherjee, D Spokes… - Eye, 2023 - nature.com
Abstract Background/Objectives To report the incidence, microbiological profile and in-vitro
antimicrobial susceptibilities of microbial keratitis (MK) in the East of England (EoE) over a 6 …

False positive microbiological results in Acanthamoeba keratitis: the importance of clinico-microbiological correlation

TL Wong, ZZ Ong, L Marelli, A Pennacchi, M Lister… - Eye, 2023 - nature.com
We read with interest the study by Hoffman et al.[1]. on diagnostic utility of culture, PCR and
in vivo confocal microscopy (IVCM) for infectious keratitis, including Acanthamoeba keratitis …

Diagnosing and monitoring the characteristics of Acanthamoeba keratitis using slit scanning and laser scanning in vivo confocal microscopy

K Curro‐Tafili, FD Verbraak, R de Vries… - Ophthalmic and …, 2024 - Wiley Online Library
Introduction Acanthamoeba keratitis (AK) is a serious and potentially blinding ocular
infection caused by the free‐living amoeba, Acanthamoeba. In vivo confocal microscopy …