Microorganisms are known as important sources of natural compounds that have been
studied and applied for different purposes in distinct areas. Specifically, in the …

The initial focus of recombinant protein production by filamentous fungi related to exploiting
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …

Antagonistic bacterial interactions often rely on antimicrobial bacteriocins, which attack only
a narrow range of target bacteria. However, antimicrobials with broader activity may be …

Fungal aromatic polyketides constitute a large family of bioactive natural products and are
synthesized by the non-reducing group of iterative polyketide synthases (PKSs). Their …

Covering: 2007 to 2011. Previous review: Nat. Prod. Rep., 2007, 24, 750 Common to all
FASs, PKSs and NRPSs is a remarkable component, the acyl or peptidyl carrier protein …

Modular polyketide synthases (type I PKSs) in bacteria are responsible for synthesizing a
significant percentage of bioactive natural products. This group of synthases has a …

High throughput genome sequencing has revealed a multitude of potential secondary
metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction coupled with …

Clonostachys rosea is a mycoparasitic fungus used for biological control of plant diseases.
Its genome contains 31 genes putatively encoding for polyketide synthases (PKSs), 75% of …

Polyketides found in nature originate from backbones synthesized through iterative
decarboxylative Claisen condensations catalysed by polyketide synthases (PKSs) …

Influenza A virus (IAV) is a severe worldwide threat to public health and economic
development due to its high morbidity and mortality. Marine-derived fungi have been …