BACKGROUND Family-planning policies have focused on contraceptive approaches to
avoid unintended pregnancies, postpone, or terminate pregnancies and mitigate population …

Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …

Background Sperm quality has decreased over the last decades worldwide. It is affected,
among others, by season and heat. This study aimed to address the association between …

Busulfan, a bifunctional alkylated chemotherapeutic agent, has male reproductive toxicity
and induce oligospermia, which is associated with ferroptosis. However, the specific target …

Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been identified as major risk factors for male reproductive health, even …

Male infertility is a global health concern. The effectiveness of interventions developed to
improve males' knowledge of fertility regulation and fertility-related risk factors remains …

Advancing healthcare for elderly men requires a deeper understanding of testicular aging
processes. In this study, we conducted transcriptomic profiling of 43,323 testicular single …

It is estimated that 15% of couples at reproductive age worldwide suffer from infertility,
approximately 50% of cases are caused by male factors. Significant progress has been …

Oxidative stress is considered one of the main challenges for in vitro maturation (IVM) and
makes assisted reproductive technology (ART), including IVF and embryonic development …

Sperm quality is declining dramatically during the past decades. Male infertility has been a
serious health and social problem. The sperm cell driven biohybrid nanorobot opens a new …