Adult stem cells at work: regenerating skeletal muscle
Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …
Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing
L Forcina, M Cosentino, A Musarò - Cells, 2020 - mdpi.com
Despite a massive body of knowledge which has been produced related to the mechanisms
guiding muscle regeneration, great interest still moves the scientific community toward the …
guiding muscle regeneration, great interest still moves the scientific community toward the …
Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
Depending on the inflammatory milieu, injury can result either in a tissue's complete
regeneration or in its degeneration and fibrosis, the latter of which could potentially lead to …
regeneration or in its degeneration and fibrosis, the latter of which could potentially lead to …
Satellite cells and the muscle stem cell niche
Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
[HTML][HTML] Skeletal muscle regeneration is modulated by inflammation
W Yang, P Hu - Journal of orthopaedic translation, 2018 - Elsevier
Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent
findings indicate that inflammatory responses could play central roles in bridging initial …
findings indicate that inflammatory responses could play central roles in bridging initial …
[PDF][PDF] Leucocytes, cytokines and satellite cells: what role do they play in muscle damage and regeneration following eccentric exercise?
Exercise-induced muscle damage is an important topic in exercise physiology. However,
several aspects of our understanding of how muscles respond to highly stressful exercise …
several aspects of our understanding of how muscles respond to highly stressful exercise …
Aberrant repair and fibrosis development in skeletal muscle
CJ Mann, E Perdiguero, Y Kharraz, S Aguilar… - Skeletal muscle, 2011 - Springer
The repair process of damaged tissue involves the coordinated activities of several cell
types in response to local and systemic signals. Following acute tissue injury, infiltrating …
types in response to local and systemic signals. Following acute tissue injury, infiltrating …
Monocyte/macrophage-derived IGF-1 orchestrates murine skeletal muscle regeneration and modulates autocrine polarization
J Tonkin, L Temmerman, RD Sampson… - Molecular therapy, 2015 - cell.com
Insulin-like growth factor 1 (IGF-1) is a potent enhancer of tissue regeneration, and its
overexpression in muscle injury leads to hastened resolution of the inflammatory phase …
overexpression in muscle injury leads to hastened resolution of the inflammatory phase …
Effect of modulating macrophage phenotype on peripheral nerve repair
Peripheral nerve repair across long gaps remains clinically challenging despite progress
made with autograft transplantation. While scaffolds that present trophic factors and …
made with autograft transplantation. While scaffolds that present trophic factors and …
[HTML][HTML] Growth factor delivery using extracellular matrix-mimicking substrates for musculoskeletal tissue engineering and repair
Therapeutic approaches for musculoskeletal tissue regeneration commonly employ growth
factors (GFs) to influence neighboring cells and promote migration, proliferation, or …
factors (GFs) to influence neighboring cells and promote migration, proliferation, or …