A review on SIRT3 and its natural small molecule activators as a potential Preventive and therapeutic target
Y Liu, H Wei, J Li - European Journal of Pharmacology, 2023 - Elsevier
Sirtuins (SIRTs) were originally characterized by yeast Sir2 as a lifespan regulator that is
conserved in all three structural domains of bacteria, archaea and eukaryotes and belong to …
conserved in all three structural domains of bacteria, archaea and eukaryotes and belong to …
Recent progress on biological production of α-arbutin
X Zhu, Y Tian, W Zhang, T Zhang, C Guang… - Applied Microbiology and …, 2018 - Springer
Arbutin, a glucoside of hydroquinone, is used as a powerful skin lightening agent in the
cosmeceutical industry because of its strong inhibitory effect on the human tyrosinase …
cosmeceutical industry because of its strong inhibitory effect on the human tyrosinase …
[HTML][HTML] The double-edged sword of SIRT3 in cancer and its therapeutic applications
S Ouyang, Q Zhang, L Lou, K Zhu, Z Li, P Liu… - Frontiers in …, 2022 - frontiersin.org
Reprogramming of cellular energy metabolism is considered an emerging feature of cancer.
Mitochondrial metabolism plays a crucial role in cancer cell proliferation, survival, and …
Mitochondrial metabolism plays a crucial role in cancer cell proliferation, survival, and …
Suppression of reactive oxygen species‐mediated ERK and JNK activation sensitizes dihydromyricetin‐induced mitochondrial apoptosis in human non‐small cell …
SJ Kao, WJ Lee, JH Chang, JM Chow… - Environmental …, 2017 - Wiley Online Library
Nonsmall cell lung cancer (NSCLC) is the most common type of lung cancer with a high
mortality rate and still remains a therapeutic challenge. A strategy for targeting NSCLC is to …
mortality rate and still remains a therapeutic challenge. A strategy for targeting NSCLC is to …
[HTML][HTML] Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells
S Wu, B Liu, Q Zhang, J Liu, W Zhou, C Wang, M Li… - PloS one, 2013 - journals.plos.org
Dihydromyricetin (DHM) is a major active ingredient of flavonoids compounds. It exhibited
anticancer activity and induced apoptosis in human hepatocellular carcinoma HepG2 cells …
anticancer activity and induced apoptosis in human hepatocellular carcinoma HepG2 cells …
GH13 amylosucrases and GH70 branching sucrases, atypical enzymes in their respective families
Amylosucrases and branching sucrases are α-retaining transglucosylases found in the
glycoside-hydrolase families 13 and 70, respectively, of the clan GH-H. These enzymes …
glycoside-hydrolase families 13 and 70, respectively, of the clan GH-H. These enzymes …
[HTML][HTML] Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast …
JA Méndez-Líter, I Tundidor, M Nieto-Domínguez… - Microbial cell …, 2019 - Springer
Background Transglycosylation represents one of the most promising approaches for
obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the …
obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the …
Recent biotechnological progress in enzymatic synthesis of glycosides
Glycosylation is one of the most important post-modification processes of small molecules
and enables the parent molecule to have increased solubility, stability, and bioactivity …
and enables the parent molecule to have increased solubility, stability, and bioactivity …
Dihydromyricetin induces mitochondria-mediated apoptosis in HepG2 cells through down-regulation of the Akt/Bad pathway
Z Zhang, H Zhang, S Chen, Y Xu, A Yao, Q Liao… - Nutrition Research, 2017 - Elsevier
The plant flavonol dihydromyricetin (DHM) was reported to induce apoptosis in human
hepatocarcinoma HepG2 cells. This study was undertaken to elucidate the underlying …
hepatocarcinoma HepG2 cells. This study was undertaken to elucidate the underlying …