Functional characterization of three flavonoid glycosyltransferases from Andrographis paniculata

Y Li, XL Li, CJS Lai, RS Wang… - Royal Society …, 2019 - royalsocietypublishing.org
Andrographis paniculata is an important traditional medicinal herb in South and Southeast
Asian countries with diverse pharmacological activities that contains various flavonoids and …

Glycosylation enables aesculin to activate Nrf2

KH Kim, H Park, HJ Park, KH Choi, RT Sadikot, J Cha… - Scientific reports, 2016 - nature.com
Abstract Since aesculin, 6, 7-dihydroxycoumarin-6-O-β-glucopyranoside, suppresses
inflammation, we asked whether its anti-inflammatory activity is associated with the …

Semi‐Synthesis of Flavonoid Glycosides and Their Anti‐Inflammatory and Antitumor Activities towards Triple Negative Breast Cancer

JZ Xie, HJ Xu, Q Zhang, Z Wu, XD Wu… - Chemistry & …, 2023 - Wiley Online Library
Background: Flavonoid glycosides are known to possess diverse bioactivities including
antitumor and anti‐inflammatory properties. Hesperetin is abundant in nature and can be …

Glycosylation enhances the physicochemical properties of caffeic acid phenethyl ester

KO Moon, S Park, M Joo, KT Ha, NI Baek… - … of Microbiology and …, 2017 - koreascience.kr
In this study, we synthesized a glycosylated derivative of caffeic acid phenethyl ester (CAPE)
using the amylosucrase from Deinococcus geothermalis with sucrose as a substrate and …

Tailoring natural products with glycosyltransferases

K Härtl, K McGraphery, J Rüdiger… - Biotechnology of natural …, 2018 - Springer
The bioactivity of plant natural products depends on more than just their scaffolds. The
physicochemical properties of the natural products are often dramatically changed by …

Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis

Q He, H Yin, J Jiang, Y Bai, N Chen, S Liu… - Journal of agricultural …, 2017 - ACS Publications
Three rosmarinic acid analogs produced by recombinant Escherichia coli, two xanthones
from fungi and honokiol from plants, were explored as the substrates of E. coli harboring a …

Antimycobacterial, antibiofilm and efflux pump inhibitory activity of extracts from selected Combretum species used in traditional medicine in Zimbabwe

SN Chikafa, CG Fru, S Mukanganyama - Advances in Traditional …, 2024 - Springer
Non-tuberculous mycobacteria infect mostly immunocompromised people. NTM infections
incidence and prevalence increase has led to a public health problem. Combretum species …

Investigation on the interaction between myricetin and dihydromyricetin with trypsin, α‐chymotrypsin, lysozyme by spectroscopy and molecular docking methods

X Meng, G Nan, B Shi, W Li, H Liu, R Lin… - …, 2022 - Wiley Online Library
The interaction between myricetin and dihydromyricetin with trypsin, α‐chymotrypsin and
lysozyme was investigated using multispectral and molecular docking methods. The results …

Successes in engineering glucansucrases to enhance glycodiversification

D Daudé, I André, P Monsan, M Remaud-Siméon - 2014 - books.rsc.org
Glucansucrases (GS) are α-transglucosylases involved in α-glucan biosynthesis. These
enzymes have been classified as glycosyltransferases by the Enzyme Commission (EC 2.4 …

Dihydromyricetin from Ampelopsis grossedentata and its derivatives: Structural characterization and anti-hepatocellular carcinoma activity

CY Liu, YY Sun, SQ Wang, YQ Jia, HX Wang… - Journal of Molecular …, 2022 - Elsevier
Dihydromyricetin (DMY) was efficiently extracted from Ampelopsis grossedentata and
modified by esterification to obtain two derivatives, which were named as benzoylated …