NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase

OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

A comprehensive review on the anti-cancer effects of oleuropein

S Rishmawi, F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …

Therapeutic influence on important targets associated with chronic inflammation and oxidative stress in cancer treatment

M Neganova, J Liu, Y Aleksandrova, S Klochkov, R Fan - Cancers, 2021 - mdpi.com
Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

[HTML][HTML] The inflammatory profile of the tumor microenvironment, orchestrated by cyclooxygenase-2, promotes epithelial-mesenchymal transition

F Gómez-Valenzuela, E Escobar… - Frontiers in …, 2021 - frontiersin.org
The tumor microenvironment (TME) corresponds to a complex and dynamic interconnection
between the extracellular matrix and malignant cells and their surrounding stroma …

Phenolic phytochemicals for prevention and treatment of colorectal cancer: A critical evaluation of in vivo studies

S De, S Paul, A Manna, C Majumder, K Pal, N Casarcia… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …

Platelets involved tumor cell EMT during circulation: communications and interventions

X Wang, S Zhao, Z Wang, T Gao - Cell Communication and Signaling, 2022 - Springer
Distant spreading of metastatic tumor cells is still the leading cause of tumor death.
Metastatic spreading is a complex process, in which epithelial-mesenchymal transition …

Resveratrol as sensitizer in colorectal cancer plasticity

A Brockmueller, A Sajeev, L Koklesova… - Cancer and Metastasis …, 2023 - Springer
Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

Viruses in colorectal cancer

L Marongiu, H Allgayer - Molecular Oncology, 2022 - Wiley Online Library
Increasing evidence suggests that microorganisms might represent at least highly
interesting cofactors in colorectal cancer (CRC) oncogenesis and progression. Still …

Overcoming therapy resistance in colon cancer by drug repurposing

T El Zarif, M Yibirin, D De Oliveira-Gomes… - Cancers, 2022 - mdpi.com
Simple Summary Despite improvements in standardized screening methods and the
development of promising therapies for colorectal cancer (CRC), survival rates are still low …

The role of the tumor microenvironment in colorectal cancer and the potential therapeutic approaches

N Zafari, F Khosravi, Z Rezaee… - Journal of Clinical …, 2022 - Wiley Online Library
Background Colorectal cancer (CRC) with a high prevalence is recognized as the fourth
most common cause of cancer‐related death globally. Over the past decade, there has been …