Lupus nephritis

HJ Anders, R Saxena, M Zhao, I Parodis… - Nature reviews Disease …, 2020 - nature.com
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

Lupus nephritis: clinical presentations and outcomes in the 21st century

M Gasparotto, M Gatto, V Binda, A Doria… - Rheumatology, 2020 - academic.oup.com
Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the
epidemiology of LN and its clinical presentation have been changing. However, even …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Update on lupus nephritis

S Almaani, A Meara, BH Rovin - … Journal of the American Society of …, 2017 - journals.lww.com
SLE is a chronic inflammatory disease that affects the kidneys in about 50% of patients.
Lupus nephritis is a major risk factor for overall morbidity and mortality in SLE, and despite …

Lupus nephritis: new progress in diagnosis and treatment

C Yu, P Li, X Dang, X Zhang, Y Mao, X Chen - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …

Treatment of lupus nephritis: consensus, evidence and perspectives

CC Mok, YKO Teng, R Saxena, Y Tanaka - Nature Reviews …, 2023 - nature.com
Despite the continuing development of immunomodulatory agents and supportive care, the
prognosis associated with lupus nephritis (LN) has not improved substantially in the past …

What is damaging the kidney in lupus nephritis?

A Davidson - Nature Reviews Rheumatology, 2016 - nature.com
Despite marked improvements in the survival of patients with severe lupus nephritis over the
past 50 years, the rate of complete clinical remission after immune suppression therapy is< …

Systemic lupus erythematosus, lupus nephritis and end-stage renal disease: a pragmatic review mapping disease severity and progression

A Mahajan, J Amelio, K Gairy, G Kaur, RA Levy… - Lupus, 2020 - journals.sagepub.com
Objective The understanding of systemic lupus erythematosus (SLE) and lupus nephritis
(LN) pathogenesis remains incomplete. This review assessed LN development in SLE …

[HTML][HTML] Management and treatment of glomerular diseases (part 2): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies …

BH Rovin, DJ Caster, DC Cattran, KL Gibson… - Kidney international, 2019 - Elsevier
In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative
brought a diverse panel of experts in glomerular diseases together to discuss the 2012 …

Histologic versus clinical remission in proliferative lupus nephritis

A Malvar, P Pirruccio, V Alberton… - Nephrology Dialysis …, 2017 - academic.oup.com
Background Treatment response in lupus nephritis (LN) is defined clinically, without
consideration of renal histology. Few studies have systematically examined histologic …