Leptomeningeal metastasis: a review of the pathophysiology, diagnostic methodology, and therapeutic landscape
A Nguyen, A Nguyen, OT Dada, PD Desai, JC Ricci… - Current …, 2023 - mdpi.com
The present review aimed to establish an understanding of the pathophysiology of
leptomeningeal disease as it relates to late-stage development among different cancer …
leptomeningeal disease as it relates to late-stage development among different cancer …
The emerging therapeutic landscape of relapsed/refractory multiple myeloma
B Tanenbaum, T Miett, SA Patel - Annals of hematology, 2023 - Springer
From a historic lens, treatment for patients with relapsed/refractory multiple myeloma (R/R
MM) has advanced significantly since the advent of immunomodulatory agents (IMiDs) in the …
MM) has advanced significantly since the advent of immunomodulatory agents (IMiDs) in the …
Typhaneoside-tetrahedral framework nucleic acids system: mitochondrial recovery and antioxidation for acute kidney injury treatment
R Yan, W Cui, W Ma, J Li, Z Liu, Y Lin - ACS nano, 2023 - ACS Publications
Acute kidney injury (AKI) is not only a worldwide problem with a cruel hospital mortality rate
but also an independent risk factor for chronic kidney disease and a promoting factor for its …
but also an independent risk factor for chronic kidney disease and a promoting factor for its …
Isatuximab, carfilzomib, and dexamethasone in patients with relapsed multiple myeloma: updated results from IKEMA, a randomized Phase 3 study
Longer-term outcomes with the anti-CD38 antibody isatuximab in combination with
carfilzomib-dexamethasone (Isa-Kd) were evaluated in the randomized Phase 3 trial IKEMA …
carfilzomib-dexamethasone (Isa-Kd) were evaluated in the randomized Phase 3 trial IKEMA …
Final analysis of carfilzomib, dexamethasone, and daratumumab vs carfilzomib and dexamethasone in the CANDOR study
CANDOR (NCT03158688) is a phase 3, randomized, open-label trial comparing carfilzomib,
daratumumab, and dexamethasone (KdD) vs carfilzomib and dexamethasone (Kd) in adults …
daratumumab, and dexamethasone (KdD) vs carfilzomib and dexamethasone (Kd) in adults …
Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma
Multiple myeloma (MM) is a plasma cell malignancy defined by complex genetics and
extensive patient heterogeneity. Despite a growing arsenal of approved therapies, MM …
extensive patient heterogeneity. Despite a growing arsenal of approved therapies, MM …
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
ZC Zeng, Q Pan, YM Sun, HJ Huang, XT Chen… - EMBO …, 2023 - embopress.org
Abstract N 6‐Methyladenosine (m6A) is an important RNA modification catalyzed by
methyltransferase‐like 3 (METTL3) and METTL14. m6A homeostasis mediated by the …
methyltransferase‐like 3 (METTL3) and METTL14. m6A homeostasis mediated by the …
Antibodies and bispecifics for multiple myeloma: effective effector therapy
C Cipkar, C Chen, S Trudel - Hematology, 2022 - ashpublications.org
The therapeutic landscape in multiple myeloma (MM) has changed dramatically over the last
2 decades. With the introduction of novel immunotherapies, patients with MM can expect …
2 decades. With the introduction of novel immunotherapies, patients with MM can expect …
Global disparities in patients with multiple myeloma: a rapid evidence assessment
There are disparities in outcomes for patients with multiple myeloma (MM). We evaluated the
influence of sociodemographic factors on global disparities in outcomes for patients with …
influence of sociodemographic factors on global disparities in outcomes for patients with …
Dracocephalum moldavica L.: An updated comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, and application aspects
M Zhan, M Ma, X Mo, Y Zhang, T Li, Y Yang, L Dong - Fitoterapia, 2023 - Elsevier
Dracocephalum moldavica, known as Xiang-qing-lan (in Chinese), is a traditional folk
medicine, which was commonly used by Mongolian and Xinjiang Uyghurs area …
medicine, which was commonly used by Mongolian and Xinjiang Uyghurs area …