Next generation strategies for preventing preterm birth
Preterm birth (PTB) is defined as delivery before 37 weeks of gestation. Globally, 15 million
infants are born prematurely, putting these children at an increased risk of mortality and …
infants are born prematurely, putting these children at an increased risk of mortality and …
Landscape of preterm birth therapeutics and a path forward
BS Coler, O Shynlova, A Boros-Rausch, S Lye… - Journal of Clinical …, 2021 - mdpi.com
Preterm birth (PTB) remains the leading cause of infant morbidity and mortality. Despite 50
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …
Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled …
MK Hoffman, SS Goudar, BS Kodkany, M Metgud… - The Lancet, 2020 - thelancet.com
Background Preterm birth remains a common cause of neonatal mortality, with a
disproportionately high burden in low-income and middle-income countries. Meta-analyses …
disproportionately high burden in low-income and middle-income countries. Meta-analyses …
Prospective evaluation of screening performance of first-trimester prediction models for preterm preeclampsia in an Asian population
P Chaemsaithong, RK Pooh, M Zheng, R Ma… - American journal of …, 2019 - Elsevier
Background The administration of aspirin< 16 weeks gestation to women who are at high
risk for preeclampsia has been shown to reduce the rate of preterm preeclampsia by 65 …
risk for preeclampsia has been shown to reduce the rate of preterm preeclampsia by 65 …
Evaluation of low-dose aspirin in the prevention of recurrent spontaneous preterm labour (the APRIL study): A multicentre, randomised, double-blinded, placebo …
AJ Landman, MA de Boer, L Visser, TAJ Nijman… - PLoS …, 2022 - journals.plos.org
Background Preterm birth is the leading cause of neonatal morbidity and mortality. The
recurrence rate of spontaneous preterm birth is high, and additional preventive measures …
recurrence rate of spontaneous preterm birth is high, and additional preventive measures …
[HTML][HTML] The role of acetylsalicylic acid in the prevention of pre-Eclampsia, fetal growth restriction, and Preterm birth
J Stubert, B Hinz, R Berger - Deutsches Ärzteblatt International, 2023 - ncbi.nlm.nih.gov
Methods This review is based on pertinent publications that were retrieved by a selective
search in PubMed, with special attention to systematic reviews, meta-analyses, and …
search in PubMed, with special attention to systematic reviews, meta-analyses, and …
[HTML][HTML] Low-dose aspirin use in pregnancy and the risk of preterm birth: a Swedish register-based cohort study
Background Preterm birth is the leading cause of neonatal mortality and morbidity. Women
who have had a previous preterm birth are at increased risk for preterm birth in their …
who have had a previous preterm birth are at increased risk for preterm birth in their …
Risk of preterm birth in relation to history of preterm birth: a population‐based registry study of 213 335 women in Norway
T Tingleff, Å Vikanes, S Räisänen… - … Journal of Obstetrics …, 2022 - Wiley Online Library
Objective To assess the association between preterm first birth and preterm second birth
according to gestational age and to determine the role of placental disorder in recurrent …
according to gestational age and to determine the role of placental disorder in recurrent …
New medicines for spontaneous preterm birth prevention and preterm labour management: landscape analysis of the medicine development pipeline
ARA McDougall, R Hastie, M Goldstein, A Tuttle… - BMC Pregnancy and …, 2023 - Springer
Background There are few medicines in clinical use for managing preterm labor or
preventing spontaneous preterm birth from occurring. We previously developed two target …
preventing spontaneous preterm birth from occurring. We previously developed two target …
First trimester risk of preeclampsia and rate of spontaneous birth in patients without preeclampsia
Background First-trimester screening for preeclampsia using a combination of maternal risk
factors and mean arterial pressure, uterine artery pulsatility index, and placental growth …
factors and mean arterial pressure, uterine artery pulsatility index, and placental growth …