Mycotoxins in a changing global environment–a review

AG Marroquín-Cardona, NM Johnson… - Food and Chemical …, 2014 - Elsevier
Mycotoxins are toxic metabolites produced by fungal species that commonly contaminate
staple foods and feeds. They represent an unavoidable problem due to their presence in …

Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry

DD De Silva, S Rapior, E Sudarman, M Stadler, J Xu… - Fungal Diversity, 2013 - Springer
Exploration of natural sources for novel bioactive compounds has been an emerging field of
medicine over the past decades, providing drugs or lead compounds of considerable …

[HTML][HTML] Ochratoxin A producing fungi, biosynthetic pathway and regulatory mechanisms

Y Wang, L Wang, F Liu, Q Wang, JN Selvaraj, F Xing… - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA), mainly produced by Aspergillus and Penicillum species, is one of the
most important mycotoxin contaminants in agricultural products. It is detrimental to human …

[HTML][HTML] The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function

LJ Klau, S Podell, KE Creamer, AM Demko… - Journal of Biological …, 2022 - ASBMB
The Natural Product Domain Seeker (NaPDoS) webtool detects and classifies ketosynthase
(KS) and condensation domains from genomic, metagenomic, and amplicon sequence data …

[HTML][HTML] Fungal toxins and host immune responses

R Brown, E Priest, JR Naglik… - Frontiers in microbiology, 2021 - frontiersin.org
Fungi are ubiquitous organisms that thrive in diverse natural environments including soils,
plants, animals, and the human body. In response to warmth, humidity, and moisture, certain …

[HTML][HTML] Advances in biodetoxification of ochratoxin AA review of the past five decades

W Chen, C Li, B Zhang, Z Zhou, Y Shen… - Frontiers in …, 2018 - frontiersin.org
Ochratoxin A (OTA) is a toxic secondary fungal metabolite that widely takes place in various
kinds of foodstuffs and feeds. Human beings and animals are inevitably threatened by OTA …

[HTML][HTML] Engineering of the Filamentous Fungus Penicillium chrysogenum as Cell Factory for Natural Products

F Guzmán-Chávez, RD Zwahlen… - Frontiers in …, 2018 - frontiersin.org
Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of
more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin …

[HTML][HTML] Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

CS Yun, T Motoyama, H Osada - Nature communications, 2015 - nature.com
Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic
fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA …

A consensus ochratoxin A biosynthetic pathway: Insights from the genome sequence of Aspergillus ochraceus and a comparative genomic analysis

Y Wang, L Wang, F Wu, F Liu, Q Wang… - Applied and …, 2018 - Am Soc Microbiol
Ochratoxin A (OTA) is a toxic secondary metabolite produced by Aspergillus and Penicillium
species that widely contaminates food and feed. We sequenced and assembled the …

[HTML][HTML] Diversity, ecology, and prevalence of antimicrobials in nature

MM Mullis, IM Rambo, BJ Baker, BK Reese - Frontiers in microbiology, 2019 - frontiersin.org
Microorganisms possess a variety of survival mechanisms, including the production of
antimicrobials that function to kill and/or inhibit the growth of competing microorganisms …