Optimizing blood pressure in neurological emergencies

JC Rose, SA Mayer - Neurocritical care, 2004 - Springer
Excessive hypertension can challenge the brain's capacity to autoregulate cerebral blood
flow, and can aggravate increased intracranial pressure (ICP) and cerebral edema …

A mouse model of intracerebral hemorrhage using autologous blood infusion

MA Rynkowski, GH Kim, RJ Komotar, ML Otten… - Nature protocols, 2008 - nature.com
The development of controllable and reproducible animal models of intracerebral
hemorrhage (ICH) is essential for the systematic study of the pathophysiology and treatment …

Temperature management in acute neurologic disorders

YK Axelrod, MN Diringer - Neurologic clinics, 2008 - Elsevier
Temperature management in acute neurologic disorders has received considerable
attention in the last 2 decades. Numerous trials of hypothermia have been performed in …

Update on intracerebral haemorrhage

JM Ferro - Journal of neurology, 2006 - Springer
Intracerebral haemorrhage (ICH) is a common and serious disease. About 1 to 2 out of 10
patients with stroke have an ICH. The mortality of ICH is higher than that of ischaemic stroke …

Emergency craniotomy in patients worsening due to expanded cerebral hematoma: to what purpose?

AA Rabinstein, JL Atkinson, EFM Wijdicks - Neurology, 2002 - AAN Enterprises
Background: Supratentorial intracerebral hematomas often are evacuated in rapidly
deteriorating patients. Surgery may prevent death but not necessarily disability. The authors …

Clinical review: Critical care management of spontaneous intracerebral hemorrhage

F Rincon, SA Mayer - Critical care, 2008 - Springer
Intracerebral hemorrhage is by far the most destructive form of stroke. The clinical
presentation is characterized by a rapidly deteriorating neurological exam coupled with …

Augmented expression of TSPO after intracerebral hemorrhage: a role in inflammation?

F Bonsack, CH Alleyne… - Journal of …, 2016 - Springer
Background Intracerebral hemorrhage (ICH) is a potentially fatal stroke subtype accounting
for 10–15% of all strokes. Despite neurosurgical intervention and supportive care, the 30 …

Factors associated with early deterioration after spontaneous intracerebral hemorrhage: a systematic review and meta-analysis

AV Specogna, TC Turin, SB Patten, MD Hill - PloS one, 2014 - journals.plos.org
Background and Purpose Spontaneous intracerebral hemorrhage (ICH) is a devastating
form of stroke with a poor prognosis overall. We conducted a systematic review and meta …

Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduction of hemorrhage volume and neurological …

P Vespa, D McArthur, C Miller, K O'Phelan, J Frazee… - Neurocritical care, 2005 - Springer
Introduction: This ia a phase-2 safety trial to demonstrate the ability of frameless stereotactic
aspiration and thrombolysis of ICH to safely remove blood. Methods: Patients with ICH in the …

Antihypertensive treatment of acute cerebral hemorrhage (ATACH) Rationale and design

AI Qureshi… - Neurocritical Care, 2007 - Springer
This trial is a multicenter open-labeled pilot trial to determine the tolerability and safety of
three escalating levels of antihypertensive treatment goals for acute hypertension in 60 …