Potential benefits of precision medicine in cardiovascular disease (CVD) include more
accurate phenotyping of individual patients with the same condition or presentation, using …

As simulation is playing an increasingly important role in medicine, providing the individual
patient with a customised diagnosis and treatment is envisaged as part of future precision …

Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …

While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

Digital twin technology is revolutionizing healthcare systems by leveraging real-time data
integration, advanced analytics, and virtual simulations to enhance patient care, enable …

Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …

Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …

Patient-specific models of blood flow in the coronary arteries have entered clinical practice
worldwide to aid in the diagnosis and management of heart disease. This technology …

The recruitment of patients for rare or complex cardiovascular diseases is a bottleneck for
clinical trials and digital twins of the human heart have recently been proposed as a viable …

We develop a methodology to create data-driven predictive digital twins for optimal risk-
aware clinical decision-making. We illustrate the methodology as an enabler for an …