PIK3CA mutations are amongst the most prevalent somatic mutations in cancer and are
associated with resistance to first-line treatment along with low survival rates in a variety of …

Glioblastoma (GBM) is the most common and aggressive form of malignant glioma. The
GBM tumor microenvironment (TME) is a complex ecosystem of heterogeneous cells and …

Long noncoding RNAs (lncRNAs) are known to regulate gene expression; however, in many
cases, the mechanism of this regulation is unknown. One novel lncRNA relevant to …

Human anterior gradient homolog 2 (AGR2) reportedly acts as an oncogene in multiple
types of cancers. As a secreted protein, the oncogenic roles of extracellular AGR2 have …

Simple Summary The biopharmaceutical industry increasingly focuses on the development
of new anticancer drugs for effective cancer therapy. Despite these efforts, the success rate …

Background Based on previous studies highlighting that the induction of cyclooxygenase-2
(COX-2) and high prostaglandin E2 (PGE2) levels contribute to the pathogenesis of …

Scarring, a prevalent issue in clinical settings, is characterized by the excessive generation
of extracellular matrix within the skin tissue. Among the numerous regulatory factors …

Alzheimer's disease (AD) is increasingly becoming a major public health concern in our
society. While many studies have explored the use of natural polyketides, alkaloids, and …

Streptococcus pneumonia is classified as a gram-positive bacterial pathogen that causes
asymptomatic or symptomatic respiratory infections. This study aimed to evaluate the effects …

Despite advances in medical technology, lung cancer still has one of the highest mortality
rates among all malignancies. Therefore, efforts must be made to understand the precise …