CC chemokines (or β-chemokines) are 28 chemotactic cytokines with an N-terminal CC
domain that play an important role in immune system cells, such as CD4+ and CD8+ …

Pancreatic cancer (PC) is exemplified by a complex immune-suppressive, fibrotic tumor
microenvironment (TME), and aberrant expression of mucins. The constant crosstalk …

Simple Summary Triple-negative breast cancer (TNBC) is the most refractory subtype of
breast cancer. Immune checkpoint inhibitor (ICI) therapy has made progress in TNBC …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) serves an important role in
maintaining plasma cholesterol levels, and fatty acid metabolism is involved in the …

Tumor-necrosis-factor-associated apoptosis-inducing ligand (TRAIL) is one of the most
promising therapeutic cytokines that selectively induce apoptosis in tumor cells. It is known …

Purpose: The aims of the present study were to explore immune-related genes (IRGs) in
stage IV colorectal cancer (CRC) and construct a prognostic risk score model to predict …

Lung adenocarcinoma (LUAD) occupies major causes of tumor death. Identifying potential
prognostic risk genes is crucial to predict the overall survival of patients with LUAD. In this …

Tumor-associated macrophages (TAMs) play an important role in tumor growth and
metastasis. However, the involvement of TAMs infiltration in pulmonary osteosarcoma (OS) …

摘要目的: 探究基质金属蛋白酶(Matrix metalloproteinases, MMPs) 抑制剂对结肠癌细胞凋亡,
免疫功能及炎性因子的影响. 方法: 取SW480 结肠癌细胞, 随机分为低表达组(将MMPs …

Multiple checkpoint mechanisms are overridden by cancer cells in order to develop into a
tumor. Neoplastic cells, while constantly changing during the course of cancer progression …