Since its initial discovery in 1994, the adipokine leptin has received extensive interest as an
important satiety factor and regulator of energy expenditure. Although produced primarily by …

The bone marrow (BM) stromal cell microenvironment contains non-hematopoietic stromal
cells called mesenchymal stromal cells (MSCs). MSCs are plastic adherent, form CFU-Fs …

Introduction Present study was to investigate hs-CRP concentration, brain structural
alterations, and cognitive function in the context of AD [Subjective cognitive decline (SCD) …

Cytokines regulate immune responses by binding to cell surface receptors, including the
common subunit beta (βc), which mediates signaling for GM-CSF, IL-3, and IL-5. Despite …

Obesity is a chronic metabolic disease mainly caused by fat accumulation. Well-recognized
anti-obesity therapies are lacking. Celastrol is a bioactive small-molecule drug extracted …

Cancer‐related fatigue is a frequent, burdensome and often insufficiently treated symptom. A
more targeted treatment of fatigue is urgently needed. Therefore, we examined biomarkers …

The aim of this study was to investigate the associations between cardiorespiratory fitness
(CRF), long-term air pollution exposure and biochemical markers of oxidative status and …

Purpose Biallelic pathogenic leptin gene variants cause severe early-onset obesity usually
associated with low or undetectable circulating leptin levels. Recently, variants have been …

In this study, the beneficial effects of EPA in ethyl esters (EE) and triacylglycerides (TAG)
forms on high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) were studied …

Obesity, a global health crisis, is associated with metabolic disorders and escalating
healthcare burdens. This review explores the multifaceted dynamics of obesity, investigating …