Apoptosis, or programmed cell death, is a normal physiologic process of cell deletion in
embryonic development as well as in the maintenance of tissue and organ homeostasis …

Targeted therapies reduce growth of mutant epidermal growth factor receptor (EGFR) non-
small cell lung cancers, but most patients develop drug resistance. This has led to efforts to …

Cancer metastasis is a multistep process that involves tumor cell migration and invasion
through tumor stroma, intravasation into and extravasation out of the blood vessels, and …

Head and neck squamous cell carcinoma (HNSCC) is characterized by the overexpression
of the epidermal growth factor receptor. However, molecular targeting strategies against …

The cyclooxygenase (COX) pathway has been implicated in carcinogenesis since the 1970s
when increased concentrations of prostaglandins were detected in neoplastic tissues …

Résumé Objectif Pendant les chirurgies du cancer, l'inflammation médiée par les
prostaglandines pourrait favoriser et activer une maladie micrométastatique avec une …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related dead worldwide
and accounts for over 85% of all lung cancers. Furthermore, the majority of patients with …

Pomimo intensywnych wysiłków i znacznych postępów poczynionych w dziedzinie leczenia
chorób nowotworowych, rak, obok chorób układu krążenia, jest nadal najistotniejszą …

زمینه و هدف: سرطان یکی از مهمترین عوامل مرگ‌ومیر در دنیا می‌باشد. به دلیل پیشرفتهای قابل توجه
در علم زیستشناسی مولکولی و سلولی، روشهای قبلی درمان سرطان با استراتژیهای جدید بهبود …‎

Purpose: Chemotherapy-induced diarrhea occurs secondary to mucosal inflammation and
may be cyclooxygenase-2 mediated. Cyclooxygenase-2 inhibitors may ameliorate …