Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering

H Tolabi, N Davari, M Khajehmohammadi… - Advanced …, 2023 - Wiley Online Library
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

[HTML][HTML] Injectable hydrogel microspheres in cartilage repair

F Lin, Y Li, W Cui - Biomedical Technology, 2023 - Elsevier
The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve
lesion repair and regeneration. However, the complex environment of the joint cavity where …

[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …

Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies

H Wang, Y Zheng, Q Sun, Z Zhang, M Zhao… - Journal of …, 2021 - Springer
Ginsenosides, the main components isolated from Panax ginseng, can play a therapeutic
role by inducing tumor cell apoptosis and reducing proliferation, invasion, metastasis; by …

Microcarriers in application for cartilage tissue engineering: Recent progress and challenges

SL Ding, X Liu, XY Zhao, KT Wang, W Xiong, ZL Gao… - Bioactive Materials, 2022 - Elsevier
Successful regeneration of cartilage tissue at a clinical scale has been a tremendous
challenge in the past decades. Microcarriers (MCs), usually used for cell and drug delivery …

Recent advances in microfluidic-aided chitosan-based multifunctional materials for biomedical applications

Y Gao, Q Ma, J Cao, Y Wang, X Yang, Q Xu… - International Journal of …, 2021 - Elsevier
Chitosan-based biomaterials has shown great advantages in a broad range of applications,
including drug delivery, clinical diagnosis, cell culture and tissue engineering. However, due …

Construction of a PEGDA/chitosan hydrogel incorporating mineralized copper-doped mesoporous silica nanospheres for accelerated bone regeneration

EM Hia, SR Jang, B Maharjan, J Park, CH Park… - International Journal of …, 2024 - Elsevier
Hydrogels, integrating diverse biocompatible materials, have emerged as promising
candidates for bone repair applications. This study presents a double network hydrogel …

Injectable composite hydrogels encapsulating gelatin methacryloyl/chitosan microspheres as ARPE-19 cell transplantation carriers

X Cheng, P Yin, T Li, L Luo, Y Yang, L Wang… - Biomaterials …, 2023 - pubs.rsc.org
Retinal pigment epithelial (RPE) cell transplantation is being explored as a feasible
approach for treating age-related macular degeneration. The low aggregation ability of RPE …

Microsphere‐containing hydrogel scaffolds for tissue engineering

S Zhang, A Lin, Z Tao, Y Fu, L Xiao… - Chemistry–An Asian …, 2022 - Wiley Online Library
Abstract Key Laboratory for Ultrafine Materials of Ministry of Education Centre for Biomedical
Technologies Current tissue engineering technology aims to achieve the regeneration of …

Opportunities and challenges of hydrogel microspheres for tendon–bone healing after anterior cruciate ligament reconstruction

X Zhao, Y Zhou, J Li, C Zhang… - Journal of Biomedical …, 2022 - Wiley Online Library
Poor angiogenesis and bony ingrowth are the major factors causing unsatisfactory healing
between the tendon graft and the bone tunnel surface. Exogenous biological factors …