Antibiotic–cell‐penetrating peptide conjugates targeting challenging drug‐resistant and intracellular pathogenic bacteria
SM Zeiders, J Chmielewski - Chemical biology & drug design, 2021 - Wiley Online Library
The failure to treat everyday bacterial infections is a current threat as pathogens are finding
new ways to thwart antibiotics through mechanisms of resistance and intracellular refuge …
new ways to thwart antibiotics through mechanisms of resistance and intracellular refuge …
Prospect of cell penetrating peptides in stem cell tracking
X Zhang, T Lei, H Du - Stem Cell Research & Therapy, 2021 - Springer
Stem cell therapy has shown great efficacy in many diseases. However, the treatment
mechanism is still unclear, which is a big obstacle for promoting clinical research. Therefore …
mechanism is still unclear, which is a big obstacle for promoting clinical research. Therefore …
The Antimicrobial Peptide MPX Can Kill Staphylococcus aureus, Reduce Biofilm Formation, and Effectively Treat Bacterial Skin Infections in Mice
C Zhu, Y Zhao, X Zhao, S Liu, X Xia, S Zhang… - Frontiers in Veterinary …, 2022 - frontiersin.org
Staphylococcus aureus is a common pathogen that can cause pneumonia and a variety of
skin diseases. Skin injuries have a high risk of colonization by S. aureus, which increases …
skin diseases. Skin injuries have a high risk of colonization by S. aureus, which increases …
Prediction of cell-penetrating potential of modified peptides containing natural and chemically modified residues
Designing drug delivery vehicles using cell-penetrating peptides is a hot area of research in
the field of medicine. In the past, number of in silico methods have been developed for …
the field of medicine. In the past, number of in silico methods have been developed for …
Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin
J Ruczyński, I Rusiecka, K Turecka, A Kozłowska… - Scientific Reports, 2019 - nature.com
In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide
(CPP) with high translocation activity, was conjugated with vancomycin (Van), which is …
(CPP) with high translocation activity, was conjugated with vancomycin (Van), which is …
A combination of a cell penetrating peptide and a protein translation inhibitor kills metastatic breast cancer cells
Abstract Cell Penetrating Peptides (CPPs) are promising anticancer and antimicrobial drugs.
We recently reported that a peptide derived from the human mitochondrial/ER membrane …
We recently reported that a peptide derived from the human mitochondrial/ER membrane …
PEP27-2, a Potent Antimicrobial Cell-Penetrating Peptide, Reduces Skin Abscess Formation during Staphylococcus aureus Infections in Mouse When Used in …
HK Kang, J Park, CH Seo, Y Park - ACS Infectious Diseases, 2021 - ACS Publications
PEP27, a 27-amino acid (aa) peptide secreted by Streptococcus pneumoniae, is an autolytic
peptide that functions as a major virulence factor. To develop a clinically applicable …
peptide that functions as a major virulence factor. To develop a clinically applicable …
Efflux pump inhibitory activity of flavonoids isolated from Alpinia calcarata against methicillin-resistant Staphylococcus aureus
HK Randhawa, KK Hundal, PN Ahirrao, SM Jachak… - Biologia, 2016 - degruyter.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium responsible for several
infections in humans. The infections caused by this bacterial strain are difficult to treat due to …
infections in humans. The infections caused by this bacterial strain are difficult to treat due to …
Exploring the possible targeting strategies of liposomes against methicillin-resistant Staphylococcus aureus (MRSA)
NNIM Rani, ZM Hussein, F Mustapa, H Azhari… - European Journal of …, 2021 - Elsevier
Multi antibiotic-resistant bacterial infections are on the rise due to the overuse of antibiotics.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the pathogens listed under the …
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the pathogens listed under the …
Computational resources in the management of antibiotic resistance: speeding up drug discovery
This article reviews more than 50 computational resources developed in past two decades
for forecasting of antibiotic resistance (AR)-associated mutations, genes and genomes. More …
for forecasting of antibiotic resistance (AR)-associated mutations, genes and genomes. More …