The microbiota-gut-brain axis: from motility to mood

KG Margolis, JF Cryan, EA Mayer - Gastroenterology, 2021 - Elsevier
The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

[HTML][HTML] The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation Global Study

AD Sperber, SI Bangdiwala, DA Drossman… - Gastroenterology, 2021 - Elsevier
Background & Aims Although functional gastrointestinal disorders (FGIDs), now called
disorders of gut-brain interaction, have major economic effects on health care systems and …

Management of functional constipation in children and adults

MH Vriesman, IJN Koppen, M Camilleri… - Nature Reviews …, 2020 - nature.com
Functional constipation is common in children and adults worldwide. Functional constipation
shows similarities in children and adults, but important differences also exist regarding …

The bacterial connection between the oral cavity and the gut diseases

S Kitamoto, H Nagao-Kitamoto, R Hein… - Journal of dental …, 2020 - journals.sagepub.com
More than 100 trillion symbiotic microorganisms constitutively colonize throughout the
human body, including the oral cavity, the skin, and the gastrointestinal tract. The oral cavity …

Prevalence of Rome IV functional bowel disorders among adults in the United States, Canada, and the United Kingdom

OS Palsson, W Whitehead, H Törnblom, AD Sperber… - Gastroenterology, 2020 - Elsevier
Background & Aims Little is known about the population prevalence or demographic
distributions of Rome IV functional bowel disorders (FBDs) or their effects on quality of life …

[HTML][HTML] Medically useful plant terpenoids: biosynthesis, occurrence, and mechanism of action

ME Bergman, B Davis, MA Phillips - Molecules, 2019 - mdpi.com
Specialized plant terpenoids have found fortuitous uses in medicine due to their
evolutionary and biochemical selection for biological activity in animals. However, these …

Intestinal barrier dysfunction in irritable bowel syndrome: a systematic review

N Hanning, AL Edwinson, H Ceuleers… - Therapeutic …, 2021 - journals.sagepub.com
Background and Aim: Irritable bowel syndrome (IBS) is a complex and heterogeneous
disorder. Sensory, motor and barrier dysfunctions are the key physiological endophenotypes …

[HTML][HTML] Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches

DJ Brayden, TA Hill, DP Fairlie, S Maher… - Advanced drug delivery …, 2020 - Elsevier
In its 33 years, ADDR has published regularly on the po5tential of oral delivery of biologics
especially peptides and proteins. In the intervening period, analysis of the preclinical and …

[HTML][HTML] Current treatment options and therapeutic insights for gastrointestinal dysmotility and functional gastrointestinal disorders

R Singh, H Zogg, UC Ghoshal, S Ro - Frontiers in pharmacology, 2022 - frontiersin.org
Functional gastrointestinal disorders (FGIDs) have been re-named as disorders of gut-brain
interactions. These conditions are not only common in clinical practice, but also in the …