Advances in venomics: Modern separation techniques and mass spectrometry
Snake venoms are complex chemical mixtures of biologically active proteins and non-
protein components. Toxins have a wide range of targets and effects to include ion channels …
protein components. Toxins have a wide range of targets and effects to include ion channels …
Isolation and characterization of ellagic acid derivatives isolated from Casearia sylvestris SW aqueous extract with anti-PLA2 activity
SL Da Silva, AK Calgarotto, JS Chaar, S Marangoni - Toxicon, 2008 - Elsevier
The Casearia sylvestris SW (Flacourtiaceae) is utilized in folk medicine (Brazil and all Latin
American) to treat several pathologic processes as inflammation, cancer, microbial infection …
American) to treat several pathologic processes as inflammation, cancer, microbial infection …
Dissection of phospholipases A2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria
MS Pena-Carrillo, EA Pinos-Tamayo, B Mendes… - Bioorganic …, 2021 - Elsevier
Cationic peptides bio-inspired by natural toxins have been recognized as an efficient
strategy for the treatment of different health problems. Due to the specific interaction with …
strategy for the treatment of different health problems. Due to the specific interaction with …
[HTML][HTML] Purification, Characterization and Evaluation of the Antitumoral Activity of a Phospholipase A2 from the Snake Bothrops moojeni
BEF Frihling, APA Boleti, CFR de Oliveira… - Pharmaceuticals, 2022 - mdpi.com
Nature presents a wide range of biomolecules with pharmacological potential, including
venomous animal proteins. Among the protein components from snake venoms …
venomous animal proteins. Among the protein components from snake venoms …
[HTML][HTML] CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and …
Snake venoms are rich and intriguing sources of biologically-active molecules that act on
target cells, modulating a diversity of physiological functions and presenting promising …
target cells, modulating a diversity of physiological functions and presenting promising …
[HTML][HTML] Distinctive Distribution of Secretory Phospholipases A2 in the Venoms of Afro-Asian Cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus)
The protein abundances of phospholipases A2 in cobra venom proteomes appear to vary
among cobra species. To determine the unique distribution of snake venom phospholipases …
among cobra species. To determine the unique distribution of snake venom phospholipases …
Anti-snake venom activities of extracts and fractions from callus cultures of Sapindus saponaria
ML da Silva, S Marcussi, RS Fernandes… - Pharmaceutical …, 2012 - Taylor & Francis
Context: Sapindus saponaria L.(Sapindaceae) bark, root, and fruits are used as sedatives
and to treat gastric ulcer and also demonstrate diuretic and expectorant effects. Objective …
and to treat gastric ulcer and also demonstrate diuretic and expectorant effects. Objective …
Isolation and functional characterization of a new acidic PLA2 Ba SpII RP4 of the Bothrops alternatus snake venom from Argentina
MEG Denegri, OC Acosta, S Huancahuire-Vega… - Toxicon, 2010 - Elsevier
An acidic protein with phospholipase A2 activity was purified to homogeneity from the
venom of the Northeast Argentinian viperid Bothrops alternatus by two chromatographic …
venom of the Northeast Argentinian viperid Bothrops alternatus by two chromatographic …
[HTML][HTML] Animal toxins: how is complexity represented in databases?
F Jungo, A Estreicher, A Bairoch, L Bougueleret… - Toxins, 2010 - mdpi.com
Peptide toxins synthesized by venomous animals have been extensively studied in the last
decades. To be useful to the scientific community, this knowledge has been stored …
decades. To be useful to the scientific community, this knowledge has been stored …
Low‐level laser therapy promotes vascular endothelial growth factor receptor‐1 expression in endothelial and nonendothelial cells of mice gastrocnemius exposed to …
DM Dourado, S Fávero, R Matias… - Photochemistry and …, 2011 - Wiley Online Library
Crotalinae snake venoms cause severe local myonecrosis and microvasculature failure at
the bite site. We evaluated whether low‐level laser therapy (LLLT) could accelerate …
the bite site. We evaluated whether low‐level laser therapy (LLLT) could accelerate …