Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

Background With the increasing rate of antibiotic resistance in Acinetobacter, the World
Health Organization introduced the carbapenem-resistant isolates in the priority pathogens …

Methicillin-resistant Staphylococcus aureus (MRSA) infections present a serious challenge
because of the emergence of resistance to numerous conventional antibiotics. Due to their …

Orthopedic implant infections are a significant clinical problem, with current therapies limited
to surgical debridement and systemic antibiotic regimens. Lysostaphin is a bacteriolytic …

Traditional methods employed to discover new antibiotics are both a time-consuming and
financially-taxing venture. This has led researchers to mine existing libraries of clinical …

Chronic wound infections caused by antibiotic-resistant bacteria have become a global
health concern. This is attributed to the biofilm-forming ability of bacteria on wound surfaces …

The increased complexity of the healing process and interplay of various pathological
factors in cutaneous wounds, in particular, chronic wounds, entails a meticulous and …

Novel antimicrobials and new approaches to developing them are urgently needed.
Repurposing already-approved drugs with well-characterized toxicology and pharmacology …

The rapid rise of bacterial resistance to traditional antibiotics combined with the decline in
discovery of novel antibacterial agents has created a global public health crisis …

Antimicrobial peptides (AMPs) represent a promising therapeutic alternative for the
treatment of antibiotic-resistant bacterial infections. The present study investigates the …