[HTML][HTML] Bone and muscle crosstalk in aging

C He, W He, J Hou, K Chen, M Huang… - Frontiers in Cell and …, 2020 - frontiersin.org
Osteoporosis and sarcopenia are two age-related diseases that affect the quality of life in the
elderly. Initially, they were thought to be two independent diseases; however, recently …

[HTML][HTML] Role of physical activity in bone–muscle crosstalk: Biological aspects and clinical implications

I Cariati, R Bonanni, F Onorato… - Journal of functional …, 2021 - mdpi.com
Bone and muscle tissues influence each other through the integration of mechanical and
biochemical signals, giving rise to bone–muscle crosstalk. They are also known to secrete …

Bone-muscle mutual interactions

N Lara-Castillo, ML Johnson - Current osteoporosis reports, 2020 - Springer
Abstract Purpose of Review The purpose of this review is to describe the current state of our
thinking regarding bone-muscle interactions beyond the mechanical perspective. Recent …

[HTML][HTML] Muscle-bone crosstalk in the masticatory system: from biomechanical to molecular interactions

S Buvinic, J Balanta-Melo, K Kupczik… - Frontiers in …, 2021 - frontiersin.org
The masticatory system is a complex and highly organized group of structures, including
craniofacial bones (maxillae and mandible), muscles, teeth, joints, and neurovascular …

Metabolic health and disease: a role of Osteokines?

A Shimonty, LF Bonewald, JR Huot - Calcified Tissue International, 2023 - Springer
Maintenance of skeletal health is tightly regulated by osteocytes, osteoblasts, and
osteoclasts via coordinated secretion of bone-derived factors, termed osteokines. Disruption …

Role of the Osteocyte in Musculoskeletal Disease

A Shimonty, LF Bonewald, F Pin - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of the Review The purpose of this review is to summarize the role of the
osteocyte in muscle atrophy in cancer patients, sarcopenia, spinal cord injury, Duchenne's …

[HTML][HTML] The role of osteokines in sarcopenia: therapeutic directions and application prospects

W Lu, W Xiao, W Xie, X Fu, L Pan, H Jin… - Frontiers in Cell and …, 2021 - frontiersin.org
Sarcopenia is an age-related disease in which muscle mass, strength and function may
decline with age or can be secondary to cachexia or malnutrition and can lead to weakness …

[HTML][HTML] Beneficial effects of denosumab on muscle performance in patients with low BMD: a retrospective, propensity score-matched study

T Rupp, E von Vopelius, A Strahl, R Oheim… - Osteoporosis …, 2022 - Springer
This study examined the effects of denosumab compared to bisphosphonates and vitamin D
alone on muscle performance in patients with low BMD. While grip force improved in both …

Role of myokines and osteokines in cancer cachexia

F Pin, LF Bonewald, A Bonetto - Experimental Biology and …, 2021 - journals.sagepub.com
Cancer-induced muscle wasting, ie cachexia, is associated with different types of cancer
such as pancreatic, colorectal, lung, liver, gastric and esophageal. Cachexia affects …

[HTML][HTML] Macrophages in skeletal muscle dystrophies, an entangled partner

M Theret, M Saclier, G Messina… - Journal of …, 2022 - content.iospress.com
While skeletal muscle remodeling happens throughout life, diseases that result in its
dysfunction are accountable for many deaths. Indeed, skeletal muscle is exceptionally …