Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …
may increase the risk for heart failure development. This risk evolves from functional and …
Autophagy in the diabetic heart: a potential pharmacotherapeutic target in diabetic cardiomyopathy
S Dewanjee, J Vallamkondu, RS Kalra, A John… - Ageing research …, 2021 - Elsevier
Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …
Increasing fatty acid oxidation prevents high-fat diet–induced cardiomyopathy through regulating parkin-mediated mitophagy
Background: Increased fatty acid oxidation (FAO) has long been considered a culprit in the
development of obesity/diabetes mellitus–induced cardiomyopathy. However, enhancing …
development of obesity/diabetes mellitus–induced cardiomyopathy. However, enhancing …
Inflammation and metabolic cardiomyopathy
K Nishida, K Otsu - Cardiovascular research, 2017 - academic.oup.com
Excessive feeding is associated with an increase in the incidence of chronic metabolic
diseases, such as obesity, insulin resistance, and type 2 diabetes. Metabolic disturbance …
diseases, such as obesity, insulin resistance, and type 2 diabetes. Metabolic disturbance …
The diabetic cardiomyopathy: the contributing pathophysiological mechanisms
T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …
[HTML][HTML] Sirt3 deficiency exacerbates diabetic cardiac dysfunction: role of Foxo3A-Parkin-mediated mitophagy
W Yu, B Gao, N Li, J Wang, C Qiu, G Zhang… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Diabetic cardiomyopathy (DCM) is often associated with suppressed cardiac autophagy,
mitochondrial structural and functional impairment. Sirtuin-3 (Sirt3) has been reported to …
mitochondrial structural and functional impairment. Sirtuin-3 (Sirt3) has been reported to …
[HTML][HTML] Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy
Diabetes is a recognized risk factor for cardiovascular diseases and heart failure. Diabetic
cardiovascular dysfunction also underscores the development of diabetic retinopathy …
cardiovascular dysfunction also underscores the development of diabetic retinopathy …
Of mice and men: models and mechanisms of diabetic cardiomyopathy
C Riehle, J Bauersachs - Basic research in cardiology, 2019 - Springer
Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension
and coronary artery disease. Although several molecular mechanisms for the development …
and coronary artery disease. Although several molecular mechanisms for the development …
Mitophagy in diabetic cardiomyopathy: roles and mechanisms
H Zheng, H Zhu, X Liu, X Huang, A Huang… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular disease is the leading complication of diabetes mellitus (DM), and diabetic
cardiomyopathy (DCM) is a major cause of mortality in diabetic patients. Multiple …
cardiomyopathy (DCM) is a major cause of mortality in diabetic patients. Multiple …
[HTML][HTML] Nrf2 signaling in diabetic nephropathy, cardiomyopathy and neuropathy: therapeutic targeting, challenges and future prospective
M Hashemi, MA Zandieh, S Ziaolhagh… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Western lifestyle contributes to an overt increase in the prevalence of metabolic anomalies
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …